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Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole

Uses of Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole

  • Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole is primarily used for managing various bacterial and parasitic infections of the vagina, such as bacterial vaginosis. It belongs to a group of medicines known as antiseptics, local anaesthetics, and antibiotics.

Side effects of Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole

  • Vaginal burning sensation

  • Mild pain in the vagina

  • Headache

  • Nausea or vomiting

  • Vaginal yeast infection

How Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole works

  • Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole is a combination medicine used to manage various bacterial and parasitic infections.

  • Chlorhexidine Gluconate is an antiseptic. It damages the cell membranes and DNA of bacteria, leading to their death. This effectively helps control bacterial infection.

  • Lidocaine, also known as Lignocaine, is a local anaesthetic. It blocks sodium channels in nerve cells. By doing this, it prevents these cells from sending pain signals to your brain, providing pain relief.

  • Metronidazole is an antibiotic. It stops the growth of bacteria and parasites by inhibiting their DNA synthesis and causing damage to their DNA. This leads to the death of the microorganism, helping clear up the infection.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage forms available

  • Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole is available mainly in the form of vaginal gels and creams.

  • These formulations are administered intravaginally, allowing direct application to the affected area.

Age and dose restrictions

  • This medicine is intended for use by adult women, especially those diagnosed with vaginal infections such as bacterial vaginosis.

Contraindications

  • Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole is contraindicated for individuals with severe liver disease.

  • It is also contraindicated in those with blood disorders like porphyria.

  • Those who have taken disulfiram in the past 14 days should not use this medicine due to the risk of severe reactions.

Other medications to avoid

  • This combination may interact with other antiseptics (such as iodine-based solutions), other local anesthetics (like bupivacaine), and other antibiotics (such as clindamycin). These interactions could affect the effectiveness and safety of the treatment.

Overdose and missed dose

  • An overdose of this medication might lead to excessive numbness due to lidocaine, or more severe neurological symptoms from metronidazole. Immediate medical attention is advised in the event of an overdose.

  • If a dose is missed, it should be used as soon as remembered unless it is nearly time for the next dose. In such cases, skip the missed dose but do not double up on the next one to avoid potential complications.

Management of side effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Apply an ice pack or cool compress to alleviate mild vaginal burning or itching.

  • Drinking plenty of fluids can help manage mild nausea or diarrhoea that might occur.

Use in driving and operating machinery

  • Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole may cause dizziness or lightheadedness. You should avoid driving or operating heavy machinery until you know how this medicine affects you.

Use in pregnancy and lactation

  • The safety of Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole during pregnancy or while breastfeeding has not been fully established. It is crucial to consult your doctor before using this medication in these conditions.

Caution in other conditions

  • Individuals with liver disease or blood disorders should use Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole with caution.

  • Those with existing nervous system disorders are advised to discuss potential risks with their doctor due to the neurological effects of metronidazole and lidocaine.

Special dietary and lifestyle recommendations

  • While using Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole, avoiding alcohol is recommended as it can interact negatively with metronidazole, causing nausea and vomiting.

  • Maintaining good personal hygiene can help prevent further infection or irritation.

  • Wearing loose-fitting, cotton underwear can reduce irritation and allow better air circulation, helping to keep the vaginal area dry and decreasing the likelihood of fungal infections.

  • Consuming probiotics through yoghurt or supplements may help maintain healthy vaginal flora and combat potential side effects like yeast infections.

Frequently asked questions

No, Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole does not typically cause weight gain. If you notice unexplained weight changes while using this medication, it might be due to other factors. Seek medical advice if you are concerned.

No, this medication does not have a known impact on hormone levels. It is an antiseptic, local anaesthetic, and antibiotic combination used to manage bacterial infections.

Before using any other remedies, including natural or herbal treatments, while taking this medication, it is crucial to discuss this with your doctor to avoid potential interactions or adverse effects.

This medication is generally safe for people with diabetes. However, if you have diabetes and prescribed this medication, ensure to monitor your blood sugar levels regularly and report any significant changes to your doctor.

This medication should not affect your mood. If you notice changes in your mood or behaviour while taking this medication, consult your doctor immediately.

No, Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole does not have any known addictive properties. It is an antiseptic and antibiotic medication and is not considered a controlled substance.

There is no evidence to suggest that this medication disrupts menstrual cycles. However, if you experience any changes in your menstrual cycle while using this medication, it's important to inform your doctor.

Terms & Conditions


Chlorhexidine Gluconate + Lidocaine / Lignocaine + Metronidazole in other salts

METRONIDAZOLEOFLOXACIN + METRONIDAZOLEMETRONIDAZOLE + NORFLOXACINMETRONIDAZOLE + TETRACYCLINEFURAZOLIDONE + METRONIDAZOLECLINDAMYCIN + CLOTRIMAZOLE + METRONIDAZOLELIDOCAINE / LIGNOCAINE + NIFEDIPINELIDOCAINE / LIGNOCAINE + METRONIDAZOLE + SUCRALFATEBECLOMETHASONE DIPROPIONATE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINELIDOCAINE / LIGNOCAINE + PRILOCAINECHLORHEXIDINE GLUCONATE + SILVER NITRATEBENZALKONIUM CHLORIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINECHLORHEXIDINE GLUCONATE + CLOBETASOL PROPIONATE + MICONAZOLE + NEOMYCINMETRONIDAZOLE + POVIDONE IODINEGABAPENTIN + LIDOCAINE / LIGNOCAINECHLORHEXIDINE GLUCONATEMETRONIDAZOLE + MUPIROCINCIPROFLOXACIN + CLOBETASOL PROPIONATE + METRONIDAZOLE + TERBINAFINECHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINECHLORHEXIDINE + LIDOCAINE / LIGNOCAINE + SILVER SULFADIAZINECHLORHEXIDINE GLUCONATE + SILVER SULFADIAZINE + SUCRALFATELIDOCAINE / LIGNOCAINE + TETRACAINECHLORHEXIDINE GLUCONATE + SILVER SULFADIAZINECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINE + TROXERUTIN + ZINC OXIDECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + ZINCCALCIUM DOBESILATE + HYDROCORTISONE ACETATE + LIDOCAINE / LIGNOCAINE + ZINCCLOTRIMAZOLE + LIDOCAINE / LIGNOCAINECETRIMIDE + CHLORHEXIDINE GLUCONATEBECLOMETHASONE DIPROPIONATE + CLOTRIMAZOLE + LIDOCAINE / LIGNOCAINE + OFLOXACINLIDOCAINE / LIGNOCAINE + PHENAZONEBECLOMETHASONE DIPROPIONATE + CHLORAMPHENICOL + CLOTRIMAZOLE + LIDOCAINE / LIGNOCAINEBECLOMETHASONE DIPROPIONATE + CLOTRIMAZOLE + LIDOCAINE / LIGNOCAINE + NEOMYCINLIDOCAINE / LIGNOCAINE + PARADICHLOROBENZENE + TURPENTINE OILBECLOMETHASONE DIPROPIONATE + CLOTRIMAZOLE + GENTAMICIN + LIDOCAINE / LIGNOCAINEBACLOFEN + GABAPENTIN + LIDOCAINE / LIGNOCAINECETRIMIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINE + TANNIC ACIDCHLORHEXIDINE GLUCONATE + METRONIDAZOLEMETRONIDAZOLE + NALIDIXIC ACIDADRENALINE + LIDOCAINE / LIGNOCAINECHLORHEXIDINE GLUCONATE + SODIUM FLUORIDE + ZINC CHLORIDEMETRONIDAZOLE + OFLOXACIN + SIMETHICONEMETRONIDAZOLE + RIFAXIMINALLANTOIN + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + ZINC OXIDECIPROFLOXACIN + METRONIDAZOLEDILOXANIDE + METRONIDAZOLE
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