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Ceftriaxone + Tazobactam

Uses of Ceftriaxone + Tazobactam

  • Ceftriaxone + Tazobactam is an antibiotic primarily used for managing various types of bacterial infections.

  • It is particularly useful in managing lower respiratory tract infections, intra-abdominal infections, skin and skin structure infections, urinary tract infections, gynaecologic infections, bacterial septicaemia, bone and joint infections, and meningitis.

Side effects of Ceftriaxone + Tazobactam

  • Diarrhoea

  • Nausea

  • Vomiting

  • Elevated blood levels of white blood cells and platelets

How Ceftriaxone + Tazobactam works

  • Ceftriaxone + Tazobactam is a combination antibiotic medicine.

  • Ceftriaxone, a third-generation cephalosporin, inhibits the formation of bacterial cell walls by blocking certain enzymes responsible for the cell wall's construction. Without a functioning cell wall, the bacteria are unable to survive, leading to their destruction.

  • Tazobactam, a beta-lactamase inhibitor, blocks bacterial enzymes called beta-lactamases, which break down antibiotics. This prevents the bacteria from inactivating Ceftriaxone and enhances its effectiveness.

  • In combination, this medicine offers a broad spectrum of antibacterial activity and is effective against many different types of bacterial infections.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ceftriaxone + Tazobactam is available as a powder that needs to be reconstituted before being used as an injection.
  • This combination medicine is intended for intravenous administration.

Age and Dose Restrictions

  • The use of Ceftriaxone + Tazobactam is suitable for both adults and children, subject to dosage adjustments.

Contraindications

  • This medicine is contraindicated in patients with a known hypersensitivity to Ceftriaxone, Tazobactam, other cephalosporins, penicillins, or beta-lactamase inhibitors.
  • It should also not be used in newborns with hyperbilirubinaemia, due to the risk of kernicterus.

Other Medications to Avoid with This Medicine

  • This combination medicine may interact with aminoglycoside antibiotics, (such as amikacin, gentamicin, and tobramycin), anticoagulants, (such as warfarin and heparin), or oral contraceptives, (such as oestradiol and ethinyl oestradiol).

Overdose and Missed Dose

  • In case of an overdose of this medicine, it may cause symptoms like severe stomach pain and shortness of breath. If you suspect an overdose, seek immediate medical assistance.
  • If you miss a dose of this medicine, get it administered as soon as you can. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dose schedule.

Management of Side Effects

Most side effects are temporary, generally harmless, and resolve once you discontinue this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water may help to manage some of the gastrointestinal side effects like diarrhoea, nausea, and vomiting.
  • Getting the medication administered after a meal may also help to reduce gastrointestinal discomfort.

Use in Driving and Operating Machinery

  • Ceftriaxone + Tazobactam does not generally affect your ability to drive or operate heavy machinery. However, if you feel dizzy or unwell after administration of the injection, refrain from these activities until you feel better.

Use in Pregnancy and Lactation

  • Ceftriaxone + Tazobactam can be used during pregnancy if needed, but only when recommended by your doctor.
  • This medicine can pass into human milk in low concentrations. Therefore, it should be used with caution while breastfeeding.

Caution in Other Conditions

  • Patients with kidney impairment should exercise caution when using this medicine, as dosage adjustments might be necessary.
  • It should also be used carefully in patients with a history of seizures, gallbladder disease, pancreatitis, liver disease, or gastrointestinal diseases such as colitis.

Special Dietary and Lifestyle Recommendation

  • Consuming a well-balanced diet rich in fruits and vegetables can boost the immune system and help fight infections.
  • Regular hand washing and maintaining proper hygiene can help prevent bacterial infections.
  • Smoking and alcohol can decrease the effectiveness of antibiotics; thus, it is advisable to limit their consumption during the treatment period.

Frequently asked questions

No, Ceftriaxone + Tazobactam is not a steroid. It is a combination antibiotic medication.

There is no evidence that Ceftriaxone + Tazobactam impacts sleep. However, if you experience sleep disturbances after using it, consider consulting your doctor.

There is no evidence of Ceftriaxone + Tazobactam affecting fertility in men or women. If you have concerns about fertility, you should discuss them with your doctor.

There are no specific food restrictions with this medicine unless specified by your doctor.

This medicine can be administered daily only if advised by your doctor.

The time it takes for this medicine to start working can vary depending on the type of infection and other individual factors. Your doctor can provide more specific information based on your condition.

This medicine is usually administered intravenously by a healthcare professional. The timing of administration will be determined by your doctor based on your condition and treatment schedule.

Terms & Conditions


Available medicines for CEFTRIAXONE + TAZOBACTAM
Tazox 1000/125 MG Injection 1
Tazox 1000/125 MG Injection 1
Lupin Ltd
Pack of 1 Units
â‚ą114.06
MRP â‚ą139.10
18.00% OFF
Xone Xp 1.125g Injection 1
Xone Xp 1.125g Injection 1
Alkem Laboratories Ltd.
Pack of 1 UNITS
â‚ą189.42
MRP â‚ą231.00
18.00% OFF
Montaz 500mg Injection 1
Montaz 500mg Injection 1
Aristo Pharmaceuticals Pvt.ltd
Pack of 1 Units
â‚ą72.16
MRP â‚ą88.00
18.00% OFF
Xone Xp Kid Injection 1
Xone Xp Kid Injection 1
Alkem Laboratories Ltd.
Pack of 1 Units
â‚ą55.76
MRP â‚ą68.00
18.00% OFF
Tazocef 250/31.25 MG Injection 1
Tazocef 250/31.25 MG Injection 1
Medley Pharmaceuticals
Pack of 1 UNITS
â‚ą37.72
MRP â‚ą46.00
18.00% OFF
Tazorax 1.125 Injection 1
Tazorax 1.125 Injection 1
Leeford Healthcare
Pack of 1 Units
â‚ą65.08
MRP â‚ą113.16
42.49% OFF
Montaz 250mg Injection 1
Montaz 250mg Injection 1
Aristo Pharmaceuticals Pvt.ltd
Pack of 1 Units
â‚ą65.60
MRP â‚ą80.00
18.00% OFF
Montaz 1gm Injection 1
Montaz 1gm Injection 1
Aristo Pharmaceuticals Pvt.ltd
Pack of 1 UNITS
â‚ą176.30
MRP â‚ą215.00
18.00% OFF

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