Carbidopa + Entacapone + Levodopa

Expert Advice

Dosage Forms Available

• Carbidopa + Entacapone + Levodopa combination is available as oral tablets. This medication is designed to be taken via the mouth, simplifying the administration process.

Age and Dose Restrictions

• This medicine is intended for use in adults. It is not typically recommended for children or adolescents, as the safety and efficacy have not been established in these age groups.

Contraindications

• Carbidopa + Entacapone + Levodopa should not be taken by patients with known hypersensitivity to any of the ingredients in this combination.

• It is contraindicated in patients with Narrow-angle glaucoma, suspicious skin lesions or a history of melanoma or pheochromocytoma, and those taking non-selective MAO inhibitors.

Other Medications to Avoid

• This combination may interact with non-selective MAO inhibitors (such as phenelzine and tranylcypromine), antihypertensives (like metoprolol and lisinopril), antipsychotics (like risperidone and clozapine), tricyclic antidepressants (like amitriptyline and nortriptyline) and medicines like isoniazid and phenytoin which can alter Levodopa bioavailability.

• Doctors should be consulted before starting any other prescription or over-the-counter medications concurrently with this combination.

Overdose and Missed Dose

• An overdose of Carbidopa + Entacapone + Levodopa may lead to severe nausea, vomiting, irregular heartbeat, muscle stiffness and unconsciousness. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose of this medicine, take it as soon as you remember. But if it is close to the time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking adequate water may help manage some gastrointestinal side effects like nausea and diarrhoea.

• For dizziness or lightheadedness, it is suggested to rise gradually from a seated or lying position.

Use in Driving and Operating Machinery

• Carbidopa + Entacapone + Levodopa may cause dizziness or drowsiness, affecting the ability to drive or operate heavy machinery. Caution is advised until you know how this medicine affects you.

Use in Pregnancy and Lactation

• Carbidopa + Entacapone + Levodopa should be used with caution during pregnancy and breastfeeding. Always consult your doctor before using this medicine during these periods.

Caution in Other Conditions

• Patients with severe cardiovascular or pulmonary disease, peptic ulcer, hepatic or renal impairment, endocrine diseases like hyperthyroidism, and a history of seizures or psychosis should exercise caution when taking Carbidopa + Entacapone + Levodopa.

Special Dietary and Lifestyle Recommendations

• A balanced diet rich in fruits, vegetables, lean proteins and healthy fats can contribute to overall health and wellbeing, supporting optimal treatment outcomes.

• Regular physical activity can help improve mood and energy levels. It can also help maintain a healthy weight.

• It is important to get adequate rest to support overall health and well-being.

• Avoid excessive intake of protein-rich foods as they may interfere with the absorption of Levodopa.

Frequently asked questions

Terms & Conditions