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Capreomycin

Uses of Capreomycin

  • Capreomycin is used to treat active tuberculosis (TB), specifically caused by capreomycin-susceptible strains of M. tuberculosis.
  • It belongs to the class of cyclic peptide antibiotics and is typically prescribed for patients whose previous TB treatments were ineffective.

Side effects of Capreomycin

  • Pain, swelling, or redness at the injection site

  • Skin rash and itching

  • Mild fever

  • Nausea and vomiting

  • Dizziness and headache

How Capreomycin works

  • Capreomycin is a cyclic peptide antibiotic.

  • It operates by hampering the synthesis of bacterial proteins. This is done by latching onto the 30S subunit of the bacterial ribosome, which hinders the interaction between messenger RNA (mRNA) and transfer RNA (tRNA). This, in turn, disrupts the assembly of amino acids into proteins that are crucial for the bacteria's growth and survival.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Capreomycin is available in the form of an injectable form. The injection is administered either through the deep intramuscular route or intravenous infusion.

Age and Dose Restrictions

  • This medication is approved for use in adults aged 18 years and older.

Contraindications

  • Capreomycin is contraindicated in patients with known hypersensitivity to the component.

  • It is also contraindicated in patients with pre-existing auditory impairment, renal insufficiency, or neuromuscular disorders such as myasthenia gravis and Parkinson's disease.

Other Medications to Avoid

  • Capreomycin may interact with aminoglycoside antibiotics (such as amikacin, gentamicin and tobramycin), loop diuretics (like furosemide and ethacrynic acid), antifungal medication (Amphotericin B), chemotherapy agents (like cisplatin) and antiviral medicines (like foscarnet).

Overdose and Missed Dose

  • Overdosing on Capreomycin can lead to serious side effects such as hearing loss, dizziness, kidney problems, and muscle weakness. If you suspect an overdose, contact your doctor immediately.

  • If you miss a dose of Capreomycin, administer it as soon as you remember. But if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

  • Take rest in a quiet, dark room to manage headache and dizziness.

  • Eat small, frequent meals to help manage nausea.

Use in Driving and Operating Machinery

  • Capreomycin may cause side effects like dizziness or loss of balance. Hence, you should avoid driving or operating heavy machinery after administering this medicine.

Use in Pregnancy and Lactation

  • Capreomycin is not recommended for use during pregnancy unless the potential benefits outweigh the risks.

  • As this medicine can pass into breast milk, it's essential to ask your doctor before using it while breastfeeding.

Caution in Other Conditions

  • Patients with kidney problems or who are on dialysis should use Capreomycin with caution.

  • Patients with hearing problems should also use this medication cautiously as it may worsen their condition.

Special Dietary and Lifestyle Recommendations

  • Ensure you maintain a balanced diet rich in essential nutrients.

  • Ensure you get regular physical exercise to maintain overall health.

Frequently asked questions

Capreomycin is an antibiotic used to treat certain types of tuberculosis. It is not commonly associated with mood changes or menstruation issues. However, side effects can vary, and if you experience any unusual symptoms related to mood or menstruation, you should contact your doctor.

If you have known hypersensitivity to Capreomycin or any of its components, it is not recommended to administer this medication. Consult your doctor for an alternative medication.

There are no known natural alternatives that can replace the activity of Capreomycin in managing multi-medicine-resistant tuberculosis. Always consult with your doctor before using alternative therapies.

The time it takes for Capreomycin to work will vary from person to person and depends on the severity of the illness. Always consult your doctor for specific information.

No, Capreomycin is not a steroid. It is an antibiotic medication from the class of cyclic peptide antibiotics.

The safety of taking Capreomycin daily depends on your health condition and the course of treatment prescribed by your doctor. Always follow your doctor's instructions regarding medication dosage and duration.

Capreomycin is not generally associated with affecting fertility. However, if you have concerns about its impact on fertility or any other side effects, it's a good idea to discuss them with your doctor.

Terms & Conditions

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