Home/Drugs By Ailments / Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc

Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc

Uses of Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc

  • Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc is primarily used for the management of internal and external haemorrhoids, and belongs to the group of vasoprotective and anti-inflammatory medications.

  • The combination can also be useful in relieving pain and discomfort associated with anal fissures, pruritus ani, and other inflammatory anorectal conditions.

Side effects of Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc

  • Burning sensation at the application site

  • Mild itching or dryness

  • Redness or irritation of the skin

  • Rare cases of allergic reactions like rash or hives

How Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc works

  • Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc is a multi-therapeutic combination.

  • Calcium Dobesilate is a vasoprotective agent. It reduces capillary permeability, inhibits platelet aggregation, and enhances blood viscosity. This helps strengthen blood vessels, decrease leakage and swelling, and improve microcirculation in the affected area.

  • Hydrocortisone Acetate is a corticosteroid. It binds to glucocorticoid receptors and triggers anti-inflammatory responses. It reduces production of inflammatory mediators, inhibits immune cell activity, and constricts dilated blood vessels, thereby alleviating itching, inflammation, and swelling.

  • Lidocaine / Lignocaine is a local anaesthetic. It blocks voltage-gated sodium channels on nerve cell membranes, preventing the generation and conduction of nerve impulses. This results in a temporary loss of sensation and pain relief in the applied area.

  • Zinc acts as a mild astringent by precipitating proteins on the skin and mucosa. Topically, it helps soothe irritated tissues, reduce secretions and promote wound healing due to its antiseptic properties. Together, these four components work synergistically to manage symptoms associated with anorectal disorders such as haemorrhoids.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc is available in topical formulations as ointments or creams, and as suppositories or gels for rectal use.

  • The medication is applied directly to the affected area or used internally via rectal insertion depending on the specific formulation.

Age and Dose Restrictions

  • This medicine is meant for adults and is generally not recommended for use by children unless prescribed by a doctor.

Contraindications

  • This combination is contraindicated in patients with known hypersensitivity to any of the ingredients.

  • It is also contraindicated in patients with bacterial, viral, or fungal infections of the anorectal area, and those with tuberculosis or syphilis affecting the anal region.

Other Medications to Avoid

  • This combination may interact with other corticosteroids (such as prednisone and dexamethasone), local anesthetics (including bupivacaine and ropivacaine), and medications affecting blood coagulation (like warfarin and heparin).

Overdose and Missed Dose

  • Overdose with Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc, applied topically, might intensify local side effects such as burning, stinging or redness. In case of accidental ingestion, symptoms like drowsiness or confusion can occur. Immediate medical attention is required in such scenarios.

  • If a dose is missed, it should be applied as soon as remembered unless it is almost time for the next application; in that case, skip the missed dose. Do not apply extra medication to make up for the missed dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If experiencing dryness or irritation at the application site, consider applying the medication at a different time of day.

  • Maintaining proper hydration may help alleviate minor irritation.

Use in Driving and Operating Machinery

  • Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc does not generally affect the ability to drive or operate heavy machinery.

Use in Pregnancy and Lactation

  • Consult a doctor before using Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc during pregnancy or while breastfeeding. The safety of its use in these conditions has not been firmly established.

Caution in Other Conditions

  • Individuals with significant inflammation or immune suppression should use this medication cautiously.

  • Patients experiencing rectal bleeding of unknown cause should consult a doctor before using this medicine.

Special Dietary and Lifestyle Recommendations

  • Increase fibre intake to help manage hemorrhoids; foods like fruits, vegetables, whole grains, and legumes can assist in softening the stool.

  • Stay hydrated by drinking plenty of water throughout the day; this helps prevent constipation, which can exacerbate hemorrhoidal discomfort.

  • Regular gentle exercise like walking can help reduce pressure on veins in the rectum and aid bowel function.

  • Avoid prolonged sitting or standing to decrease pressure on rectal veins.

  • Utilise proper techniques when lifting heavy objects to avoid straining that can worsen hemorrhoids.

Frequently asked questions

No, this medicine is specifically formulated for anorectal disorders such as hemorrhoids and anal fissures. Using it for other skin conditions may not be beneficial and could potentially cause harm. Always use medications as directed by your doctor.

This combination has several components that work together. Lidocaine numbs the area to relieve pain, hydrocortisone reduces inflammation and itching, calcium dobesilate strengthens vein walls and reduces swelling, and zinc aids in wound healing and infection prevention.

There are some people who should not use this medicine. It is contraindicated in patients with known hypersensitivity to any of its ingredients. It should also be used with caution in certain conditions, and it is recommended to consult a doctor before use.

Yes, mild burning or stinging on application is a common side effect of this medication and should subside after a few moments. If the sensation persists or worsens, discontinue use and consult your doctor.

The medication is typically applied as directed by your doctor.

Yes, Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine/Lignocaine + Zinc can be used during old age, but it’s important to use it under a doctor's supervision to monitor for potential side effects, especially due to the presence of hydrocortisone and lidocaine.

Though rare, allergic reactions such as rash or hives can occur. If you experience any symptoms of an allergic reaction, discontinue use and seek immediate medical attention.

Terms & Conditions


Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc in other salts

ASCORBIC ACID + BIOTIN + CALCIUM PANTOTHENATE + FOLIC ACID + METHYLCOBALAMIN + NIACINAMIDE + RIBOFLAVIN + THIAMINE MONONITRATE + ZINC SULPHATEASCORBIC ACID + ELEMENTAL MANGANESE + ELEMENTAL SELENIUM + ELEMENTAL ZINC + FOLIC ACID + NIACINAMIDE + PYRIDOXINE HYDROCHLORIDE + RIBOFLAVIN / VITAMIN B2 + VITAMIN A + VITAMIN EBIOTIN + CALCIUM PANTOTHENATE + COPPER SULPHATE + COPPER SULPHATE PENTAHYDRATE + CYANOCOBALAMIN / VITAMIN B12 + FERROUS SULPHATE + MAGNESIUM OXIDE + MAGNESIUM SULPHATE MONOHYDRATE + NICOTINAMIDE + PYRIDOXINE HYDROCHLORIDE + RIBOFLAVIN / VITAMIN B2 + SODIUM BORATE + SODIUM MOLYBDATE DIHYDRATE + THIAMINE MONONITRATE + TOCOPHERYL ACETATE + TOTAL PHOSPHOROUS + TRIBASIC CALCIUM PHOSPHATE + VITAMIN A / RETINOL + VITAMIN C / ASCORBIC ACID + VITAMIN D3 (CHOLECALCIFEROL) + ZINC SULPHATEBIOTIN + CYANOCOBALAMIN / VITAMIN B12 + ELEMENTAL CHROMIUM + ELEMENTAL COPPER + ELEMENTAL MANGANESE + FOLIC ACID + GRAPE SEED EXTRACT + IODINE + MAGNESIUM + RIBOFLAVIN / VITAMIN B2 + SELENIUM + THIAMINE / VITAMIN B1 + VITAMIN A / RETINOL + VITAMIN B3 / NIACIN + VITAMIN B5 / PANTOTHENIC ACID + VITAMIN B6 / PYRIDOXINE + VITAMIN C / ASCORBIC ACID + VITAMIN D3 (CHOLECALCIFEROL) + VITAMIN E + ZINCCALCIUM PHOSPHATE + COPPER SULPHATE PENTAHYDRATE + CYANOCOBALAMIN / VITAMIN B12 + D-PANTHENOL + FOLIC ACID + LIGHT MAGNESIUM OXIDE + NICOTINAMIDE + POTASSIUM IODIDE + VITAMIN A + VITAMIN B1 + VITAMIN B2 + VITAMIN D3 (CHOLECALCIFEROL) + ZINC SULPHATE MONOHYDRATECHROMIUM PICOLINATE + CYANOCOBALAMIN + ELEMENTAL SELENIUM + FOLIC ACID + NICOTINAMIDE + PYRIDOXINE HYDROCHLORIDE + ZINC SULPHATE MONOHYDRATEKETOCONAZOLE + PYRITHIONE ZINCCALCIUM DOBESILATECALCITRIOL + CALCIUM CARBONATE + ZINCKETOCONAZOLE + ZINC PYRITHIONEZINCCALCITRIOL/ CHOLECALCIFEROL + ELEMENTAL CALCIUM + ZINCNON HEMOGLOBIN + ZINCZINC ACETATECARBONYL IRON + FOLIC ACID + ZINC SULPHATECALCITRIOL/ CHOLECALCIFEROL + ELEMENTAL CALCIUM + MAGNESIUM + ZINCFOLIC ACID + IRON + ZINCRABEPRAZOLE + ZINC CARNOSINECALCITRIOL/ CHOLECALCIFEROL + CALCIUM CITRATE MALEATE + MAGNESIUM OXIDE + ZINC OXIDEFERROUS FUMARATE + FOLIC ACID + ZINC SULPHATECARBONYL IRON + CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + ZINC SULPHATECYANOCOBALAMIN / VITAMIN B12 + ELEMENTAL IRON + FOLIC ACID + VITAMIN C / ASCORBIC ACID + ZINCCYANOCOBALAMIN / VITAMIN B12 + ELEMENTAL IRON + ELEMENTAL ZINC + FOLIC ACIDCARBONYL IRON + CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + VITAMIN C / ASCORBIC ACID + ZINC SULPHATEELEMENTAL SELENIUM + ELEMENTAL ZINC + LYCOPENE + VITAMIN A / RETINOL + VITAMIN C / ASCORBIC ACID + VITAMIN EALPHA LIPOIC ACID + CHROMIUM PICOLINATE + FOLIC ACID + INOSITOL + METHYLCOBALAMIN + SELENOMETHIONINE + ZINC MONOMETHIONINECYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + IRON + ZINCASTAXANTHIN + COENZYME Q10 / UBIDECARENONE + ELEMENTAL ZINC + L-CARNITINE / LEVOCARNITINE + LYCOPENECALCITRIOL/ CHOLECALCIFEROL + ELEMENTAL CALCIUM + ELEMENTAL ZINCCYANOCOBALAMIN / VITAMIN B12 + FERROUS FUMARATE + FOLIC ACID + ZINC SULPHATEELEMENTAL IRON + ELEMENTAL ZINC + FOLIC ACIDADENOSYLCOBALAMIN + CARBONYL IRON + FOLIC ACID + ZINC SULPHATEBETA-CAROTENE + COPPER + MANGANESE + SELENIUM DIOXIDE + ZINC SULPHATE MONOHYDRATELYCOPENE + SELENIUM + VITAMIN A / RETINOL + VITAMIN C / ASCORBIC ACID + VITAMIN E + ZINC SULPHATECOPPER + LUTEIN + VITAMIN C / ASCORBIC ACID + VITAMIN E + ZEAXANTHIN + ZINCCALCIUM CITRATE MALEATE + ELEMENTAL MAGNESIUM + ELEMENTAL ZINC + VITAMIN D3 (CHOLECALCIFEROL)COENZYME Q10 / UBIDECARENONE + ELEMENTAL SELENIUM + ELEMENTAL ZINC + L ARGININE + OMEGA 3 FATTY ACIDCOENZYME Q10 / UBIDECARENONE + L-CARNITINE + LYCOPENE + ZINCELEMENTAL IRON + ELEMENTAL ZINC + FOLIC ACID + METHYLCOBALAMINZINC GLUCONATECALCITRIOL/ CHOLECALCIFEROL + CALCIUM CARBONATE + L METHYLFOLATE + MAGNESIUM + METHYLCOBALAMIN + VITAMIN K27 + ZINCFERROUS ASCORBATE + FOLIC ACID + ZINC SULPHATELIDOCAINE / LIGNOCAINE + NIFEDIPINELIDOCAINE / LIGNOCAINE + METRONIDAZOLE + SUCRALFATEBECLOMETHASONE DIPROPIONATE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINELIDOCAINE / LIGNOCAINE + PRILOCAINEBETAMETHASONE + ZINCBENZALKONIUM CHLORIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINEZINC OXIDEGABAPENTIN + LIDOCAINE / LIGNOCAINECHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINECHLORHEXIDINE + LIDOCAINE / LIGNOCAINE + SILVER SULFADIAZINECALAMINE + CETRIMIDE + CHLOROCRESOL + DIMETHICONE + SUCRALFATE + ZINC OXIDELIDOCAINE / LIGNOCAINE + TETRACAINEBORIC ACID + ZINC OXIDEBENZALKONIUM CHLORIDE + ZINC OXIDECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINE + TROXERUTIN + ZINC OXIDECHLORHEXIDINE GLUCONATE + LIDOCAINE / LIGNOCAINE + METRONIDAZOLECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + ZINCCLOTRIMAZOLE + LIDOCAINE / LIGNOCAINECLOBETASOL PROPIONATE + MICONAZOLE + NEOMYCIN + ZINC SULPHATE MONOHYDRATEBECLOMETHASONE DIPROPIONATE + CLOTRIMAZOLE + LIDOCAINE / LIGNOCAINE + OFLOXACINLIDOCAINE / LIGNOCAINE + PHENAZONEBECLOMETHASONE DIPROPIONATE + CHLORAMPHENICOL + CLOTRIMAZOLE + LIDOCAINE / LIGNOCAINEELEMENTAL ZINCZINC SULPHATEBECLOMETHASONE DIPROPIONATE + CLOTRIMAZOLE + LIDOCAINE / LIGNOCAINE + NEOMYCINLIDOCAINE / LIGNOCAINE + PARADICHLOROBENZENE + TURPENTINE OILBECLOMETHASONE DIPROPIONATE + CLOTRIMAZOLE + GENTAMICIN + LIDOCAINE / LIGNOCAINEBACLOFEN + GABAPENTIN + LIDOCAINE / LIGNOCAINECETRIMIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINE + TANNIC ACIDALUM + SODIUM MONOFLUOROPHOSPHATE + ZINC SULPHATEAVOBENZONE + OCTINOXATE + OXYBENZONE + ZINC OXIDEAVOBENZONE + OCTINOXATE + OCTOCRYLENE + OXYBENZONE + ZINC OXIDECETRIMIDE + TANNIC ACID + ZINC CHLORIDEFOLIC ACID + L ARGININE + ZINCADRENALINE + LIDOCAINE / LIGNOCAINEVITAMIN C / ASCORBIC ACID + ZINCCHLORHEXIDINE GLUCONATE + SODIUM FLUORIDE + ZINC CHLORIDECHLORHEXIDINE + SODIUM FLUORIDE + ZINC CHLORIDEELEMENTAL CALCIUM + ELEMENTAL MAGNESIUM + ELEMENTAL ZINC + VITAMIN D3 (CHOLECALCIFEROL)ELEMENTAL CALCIUM + ELEMENTAL MAGNESIUM + ELEMENTAL PHOSPHOROUS + ELEMENTAL ZINC + VITAMIN D3 (CHOLECALCIFEROL)ASCORBIC ACID + DEXTROSE + SUCROSE(SWEETNER) + ZINC SULPHATEVITAMIN C / ASCORBIC ACID + VITAMIN D3 (CHOLECALCIFEROL) + ZINCELEMENTAL ZINC + FOLIC ACID + L ARGININE + PROANTHOCYANIDINBACILLUS CLAUSII + ZINCELEMENTAL ZINC + LACTIC ACID BACILLUS + SACCHAROMYCES BOULARDII LYOPHILIZEDSERTACONAZOLE + ZINC PYRITHIONECICLOPIROX + ZINC PYRITHIONELULICONAZOLE + SALICYLIC ACID + ZINC PYRITHIONECALCIUM CITRATE + ELEMENTAL ZINC + VITAMIN D3 (CHOLECALCIFEROL)CALCITRIOL/ CHOLECALCIFEROL + CALCIUM CITRATE + MAGNESIUM + ZINCCALCITRIOL/ CHOLECALCIFEROL + CALCIUM CITRATE + MAGNESIUM OXIDE + ZINCALLANTOIN + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + ZINC OXIDEELEMENTAL CALCIUM + ELEMENTAL MAGNESIUM + ELEMENTAL ZINC + PHOSPHORUS + VITAMIN D3 (CHOLECALCIFEROL)BETA-CAROTENE + BIOTIN + CALCITRIOL/ CHOLECALCIFEROL + CHROMIUM + CYANOCOBALAMIN / VITAMIN B12 + INOSITOL + IODINE + LYSINE + MANGANESE + MOLYBDENUM + NIACINAMIDE + SELENIUM + VITAMIN B6 / PYRIDOXINE + ZINCCYANOCOBALAMIN + ELEMENTAL IRON + ELEMENTAL ZINC + FOLIC ACIDCYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + SODIUM FEREDETATE + ZINC SULPHATEELEMENTAL ZINC + FERROUS ASCORBATE + FOLIC ACIDCALCIUM CITRATE + ELEMENTAL MAGNESIUM + ELEMENTAL ZINC + VITAMIN D3 (CHOLECALCIFEROL)CHROMIUM PICOLINATE + CYANOCOBALAMIN + ELEMENTAL SELENIUM + FOLIC ACID + NICOTINAMIDE + VITAMIN B6 / PYRIDOXINE + ZINC SULPHATE MONOHYDRATECOENZYME Q10 / UBIDECARENONE + L-CARNITINE / LEVOCARNITINE + LYCOPENE + ZINCCALCITRIOL/ CHOLECALCIFEROL + ELEMENTAL CALCIUM + ELEMENTAL MAGNESIUM + ELEMENTAL ZINC + VITAMIN K27CALCIUM CITRATE + ELEMENTAL ZINC + MAGNESIUM HYDROXIDE (MILK OF MAGNESIA) + VITAMIN D3 (CHOLECALCIFEROL)CALCITRIOL/ CHOLECALCIFEROL + CALCIUM ASPARTATE + CALCIUM OROTATE + FOLIC ACID + HYDROXOCOBALAMIN + MAGNESIUM HYDROXIDE (MILK OF MAGNESIA) + ZINCCALCIUM + VITAMIN D3 (CHOLECALCIFEROL) + ZINCFERROUS ASCORBATE + FOLIC ACID + ZINCFERROUS ASCORBATE + FOLIC ACID + ZINC SULPHATE MONOHYDRATEACETYLCYSTEINE + BIOTIN + CALCIUM PANTOTHENATE + ELEMENTAL COPPER + ELEMENTAL SELENIUM + ELEMENTAL ZINCBIOTIN + CALCIUM PANTOTHENATE + ELEMENTAL COPPER + ELEMENTAL SELENIUM + ELEMENTAL ZINC + N-ACETYLCYSTEINECALCIUM CITRATE + MAGNESIUM + VITAMIN D3 (CHOLECALCIFEROL) + ZINCFERROUS BISGLYCINATE + FOLIC ACID + METHYLCOBALAMIN + ZINC BISGLYCINATECALCIUM DOBESILATE + EUPHORBIA PROSTRATECYANOCOBALAMIN + ELEMENTAL IRON + FOLIC ACID + ZINCCALCIUM CITRATE + MAGNESIUM + VITAMIN D3 (CHOLECALCIFEROL) + ZINC SULPHATECALCIUM CITRATE MALEATE + MAGNESIUM OXIDE + VITAMIN D3 (CHOLECALCIFEROL) + VITAMIN K27 + ZINC OXIDEVITAMIN C / ASCORBIC ACID + ZINC SULPHATEZINC SULPHATE MONOHYDRATEASCORBIC ACID + ELEMENTAL ZINC + SODIUM ASCORBATECALCIUM CITRATE MALEATE + MAGNESIUM SULPHATE + VITAMIN D3 (CHOLECALCIFEROL) + ZINC SULPHATE
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