Caffeine + Chlorpheniramine Maleate + Paracetamol/Acetaminophen + Phenylephrine is primarily used for managing symptoms associated with the common cold, flu and other upper respiratory allergies. It belongs to the group of over-the-counter cold and allergy medicines.
Secondary uses of this combination medication may include relieving minor aches and pains due to headaches or muscle strains.
Drowsiness
Dizziness
Nervousness
Dry mouth
Mild increases in blood pressure
Caffeine is a mild stimulant that enhances the pain-relief effects of acetaminophen and reduces drowsiness caused by chlorpheniramine.
Chlorpheniramine Maleate is an antihistamine. It works by reducing the effects of histamine, a chemical in the body that can cause symptoms such as sneezing, itching, watery eyes, and a runny nose.
Paracetamol/Acetaminophen acts as a pain reliever (analgesic) and fever reducer (antipyretic) by blocking the production of chemicals that cause pain, fever and inflammation in the body.
Phenylephrine is a decongestant. It constricts blood vessels in the nasal passages, which reduces swelling and congestion, making it easier to breathe.
Doctor of Medicine
BMS, FMC, MD Resident
Caffeine + Chlorpheniramine Maleate + Paracetamol/Acetaminophen + Phenylephrine can be taken orally (tablet).
This combination medicine is suitable for adults and children over the age of 12 years.
This medicine should not be used by individuals who have severe high blood pressure, or coronary artery disease or have taken an MAO inhibitor within the last 14 days. Additionally, those with known allergies to any of the active ingredients contained within – acetaminophen, chlorpheniramine, phenylephrine or caffeine – should also avoid this combination.
The Caffeine + Chlorpheniramine Maleate + Paracetamol/Acetaminophen + Phenylephrine combination may interact with MAO inhibitors (such as selegiline and phenelzine), blood thinners (like warfarin, heparin), tricyclic antidepressants (including amitriptyline and nortriptyline), and beta-blockers (such as atenolol and propranolol).
Overdose of this medication may lead to severe liver damage due to the acetaminophen component. If an overdose is suspected, immediately seek medical help.
In case a dose is missed, it should be taken as soon as remembered. However, if it is almost time for the next dose, skip the missed dose to prevent doubling up.
Most side effects of this medicine are transient and may go away once the medication is discontinued. If you experience severe side effects or worsening of any symptoms, it is advised to consult your doctor.
For mild increases in blood pressure, try relaxing and reducing stress.
For dry mouth, nose, or throat, stay well hydrated by drinking plenty of fluids.
This medicine may cause drowsiness and dizziness. As such, driving or operating heavy machinery should be avoided unless you are sure how this medicine affects you.
Always consult your doctor before taking any medication during these periods.
Extra care should be taken for patients with pre-existing conditions like high blood pressure, diabetes, glaucoma, or an overactive thyroid. Consult your doctor before starting this medication if you have any such conditions.
Practise good hygiene habits such as washing hands regularly and avoiding close contact with sick individuals to prevent infection spread.
Frequently asked questions
No, this combination is not a steroid. It is a combination of an analgesic (pain reliever), an antipyretic (fever reducer), an antihistamine (allergy medicine) and a decongestant.
Generally, this medication should not interact with most multivitamins. However, it is always advisable to consult your doctor before starting any new medications.
As this medication contains caffeine, consuming additional caffeine from sources like coffee could potentially lead to side effects like increased heart rate or nervousness. It is advisable to limit your caffeine intake while taking this medicine.
While some natural remedies might relieve certain cold and flu symptoms, they may not be as effective as this combination medication. You should always consult your doctor for the most appropriate treatment for your condition.
Yes, this combination does not contain aspirin. However, if you have any known allergies to any of the active ingredients in this medication, it is advised not to take it without consulting your doctor.
Caffeine + Chlorpheniramine Maleate + Paracetamol/Acetaminophen + Phenylephrine is not typically associated with affecting fertility. However, consult with your doctor for personalised advice.
The availability of this medication can vary by country and region. Some places may allow for over-the-counter purchases, whereas others may require a prescription. It is best to consult with a local pharmacy or your doctor.
Caffeine + Chlorpheniramine Maleate + Paracetamol/acetaminophen + Phenylephrine in other salts
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