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Butorphanol

Uses of Butorphanol

  • Butorphanol is primarily used for managing moderate to severe pain. It belongs to the group of medicines known as synthetic opioid analgesics.

  • Secondary uses of Butorphanol include treatment of postoperative pain and migraine headaches, pre-anaesthetic medication and suppression of post-anaesthesia shaking, relief of postpartum pain during labour and management of pain associated with muscle and bone disorders, such as toothaches.

Side effects of Butorphanol

  • Nausea

  • Vomiting

  • Constipation

  • Dizziness

  • Sedation

How Butorphanol works

  • Butorphanol is a synthetic opioid analgesic that belongs to the phenanthrene series.

  • Butorphanol acts as a mixed agonist-antagonist at opioid receptors, with low activity at mu-opioid receptors and agonist action at kappa-opioid receptors.

  • By interacting with these receptors, it reduces pain perception and has a lower risk of respiratory depression compared to pure mu-opioid agonists.

  • This mechanism of action makes Butorphanol an effective medication for managing moderate to severe pain, offering advantages over traditional opiates in certain situations.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Butorphanol is available for use in two main formulations: as an injectable solution and as a nasal spray.

  • The injectable solution of Butorphanol is administered through the intramuscular or intravenous route.

  • The nasal spray allows for administration through the nasal mucosa, providing an alternative method of delivery for patients.

Age and Dose Restrictions

  • This medicine is intended predominantly for adult use.

Contraindications

  • This medicine is contraindicated in patients with respiratory depression without resuscitative equipment.

  • It is also contraindicated in patients who are currently in treatment with monoamine oxidase inhibitors (MAOIs).

Other Medications to Avoid

  • Butorphanol may interact with central nervous system (CNS) depressants (such as alcohol, benzodiazepines like diazepam, and barbiturates like phenobarbital), opioid agonists (such as morphine and fentanyl), and other mixed agonist/antagonist opioids (like pentazocine and nalbuphine).

Overdose and Missed Dose

  • An overdose of Butorphanol can lead to severe sedation, respiratory depression, and potentially fatal respiratory arrest. Immediate medical attention is critical.

  • If you miss a dose of Butorphanol, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage dizziness or drowsiness, consider taking this medicine at a time when these effects will be less disruptive, such as before bedtime.

  • If experiencing constipation, increase your intake of dietary fibre and fluids unless advised otherwise by your doctor.

Use in Driving and Operating Machinery

  • Butorphanol may impair your ability to drive or operate heavy machinery. Avoid engaging in these activities if you feel dizzy or are not fully alert after taking this medicine.

Use in Pregnancy and Lactation

  • It is advisable to consult your doctor before using Butorphanol during pregnancy or while breastfeeding. The safety of this medicine for use in these conditions has not been firmly established.

Caution in Other Conditions

  • Patients with hepatic or renal impairment should use Butorphanol with caution due to potential changes in the medicine's clearance and activity.

  • Caution is also advised for individuals with head injuries or increased intracranial pressure.

Special Dietary and Lifestyle Recommendations

  • For patients managing pain, maintaining a well-balanced diet rich in vitamins and minerals can aid overall health and recovery. Include plenty of fruits, vegetables, whole grains, and lean proteins.

  • Engage in gentle physical activities such as walking or yoga as recommended by your healthcare provider to maintain mobility and reduce the risk of stiffness or muscle weakness during periods of reduced activity due to pain.

  • Ensure adequate hydration by drinking enough water throughout the day unless advised otherwise due to specific medical conditions.

  • Consider implementing relaxation techniques like deep breathing exercises or meditation to help manage stress that could potentially exacerbate pain symptoms.

Frequently asked questions

No, Butorphanol is not a steroid. It is an opioid analgesic, specifically a synthetic one. It belongs to the class of medications known as phenanthrene series.

Yes, Butorphanol can cause drowsiness and sedation, which may affect sleep patterns. This is a common side effect of many opioid analgesics.

There is no specific research data available that suggests Butorphanol directly affects fertility. However, if you have concerns about fertility, it is always advisable to consult your doctor.

No specific diet restrictions have been mentioned in the research data with respect to taking Butorphanol. However, it is always recommended to maintain a healthy and balanced diet.

Butorphanol should be taken as per the doctor's prescription and for the duration suggested by the doctor. It should not be consumed beyond the prescribed period or in excess quantities because of its potential for dependency and withdrawal symptoms.

After intramuscular injection, peak levels of Butorphanol in blood are typically reached within 20-40 minutes. Therefore, pain relief usually begins within this time frame.

The duration of treatment with Butorphanol will depend on your specific condition, the severity of your pain, and your doctor's instructions.

Terms & Conditions

Available medicines for BUTORPHANOL
Butrum 1 MG Injection 1 ML
Butrum 1 MG Injection 1 ML
Aristo Pharmaceuticals Pvt.ltd
Pack of 1 ML
₹18.70
MRP ₹22.81
18.00% OFF
Butrum 1 MG Injection 5 ML
Butrum 1 MG Injection 5 ML
Aristo Pharmaceuticals Pvt.ltd
Pack of 5 ML
₹93.52
MRP ₹114.05
18.00% OFF
Butodol 2 MG Injection 1 ML
Butodol 2 MG Injection 1 ML
Neon Laboratories Ltd
Pack of 1 ML
₹41.49
MRP ₹50.60
18.00% OFF
Butrum 2 MG Injection 1 ML
Butrum 2 MG Injection 1 ML
Aristo Pharmaceuticals Pvt.ltd
Pack of 1 ML
₹31.18
MRP ₹38.03
18.00% OFF
Butrum 10 MG Nasal Spray 2.5 ML
Butrum 10 MG Nasal Spray 2.5 ML
Aristo Pharmaceuticals Pvt.ltd
Pack of 2.5 ML
₹318.65
MRP ₹388.60
18.00% OFF
Butodol 1 MG Injection 1 ML
Butodol 1 MG Injection 1 ML
Neon Laboratories Ltd
Pack of 1 ML
₹29.68
MRP ₹36.20
18.00% OFF
Butrum 2 MG Injection 5 ML
Butrum 2 MG Injection 5 ML
Aristo Pharmaceuticals Pvt.ltd
Pack of 5 ML
₹155.92
MRP ₹190.15
18.00% OFF

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