Busulfan

Expert Advice

Dosage Forms Available

• Busulfan comes in the form of oral tablets, which are taken by mouth.

• It also comes as an intravenous injection, which is administered directly into a vein.

Age and Dose Restrictions

• Busulfan is primarily intended for use in adults.

• The medicine can also be prescribed to children, but the age limit and dose depend on the specific condition being treated and the child's body weight.

Contraindications

• Busulfan is contraindicated in patients with a known hypersensitivity to it or any of its components.

• Patients with severe bone marrow suppression should not take this medicine.

Other Medications to Avoid

• Busulfan may interact with antifungal medicines (such as itraconazole), anti-seizure medicines (like phenytoin), pain relievers (such as acetaminophen), antibiotics (like metronidazole), and other chemotherapy agents (e.g., cyclophosphamide, melphalan).

• Before starting any new prescription or over-the-counter medications, it is crucial to consult a doctor to avoid potential interactions.

Overdose and Missed Dose

• An overdose of Busulfan may cause severe side effects such as seizures, lung problems, liver problems, and severe infections. If you suspect an overdose, seek immediate medical attention.

• If you forget to take a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one and continue your regular schedule. Do not double up on doses to make up for a missed one.

Management of Side Effects

Most side effects of Busulfan are temporary and generally harmless, but they can be resolved when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage nausea and vomiting.

• Resting and taking short naps throughout the day can help manage fatigue.

• Mouth sores can be managed by maintaining good oral hygiene and using a soft toothbrush to prevent further irritation.

Use in Driving and Operating Machinery

• Busulfan may cause dizziness or fatigue in some patients. If you experience these side effects, avoid driving or operating heavy machinery until you feel well enough to do so.

Use in Pregnancy and Lactation

• Busulfan can harm an unborn baby and is not recommended during pregnancy.

• It is not known whether this medicine passes into breast milk. Therefore, breastfeeding should be avoided during treatment with Busulfan.

Caution in Other Conditions

• Patients with liver disease should use Busulfan with caution, as it can cause liver toxicity.

• Those with a history of seizures should also exercise caution when using this medicine, as it may increase the risk of seizure activity.

Special Dietary and Lifestyle Recommendations

• A healthy, balanced diet rich in fruits, vegetables, lean proteins, and whole grains can help maintain overall health while receiving chemotherapy.

• Regular light exercise, such as walking or yoga, may help manage fatigue related to chemotherapy.

• Adequate hydration is essential during chemotherapy to help manage side effects such as nausea and vomiting.

• Regular rest periods are important to manage fatigue associated with chemotherapy.

• Avoiding exposure to infection is crucial during chemotherapy as it can suppress the immune system. This includes avoiding crowds and people who are sick, washing hands regularly, and keeping wounds clean and covered.

Frequently asked questions

Terms & Conditions