Bromocriptine
Uses of Bromocriptine
The primary use of Bromocriptine is for the management of disorders associated with elevated prolactin levels (hyperprolactinemia), such as abnormal breast milk production (galactorrhea), absence of menstrual periods (amenorrhea), and infertility. Bromocriptine belongs to the group of medicines known as dopamine receptor agonists.
It is also effective in managing prolactin-secreting pituitary tumours (prolactinomas), reducing tumour size and normalising prolactin levels. Additionally, Bromocriptine is used for the management of Parkinson's disease symptoms and acromegaly and as an adjunct treatment for type 2 diabetes.
Side effects of Bromocriptine
Nausea and vomiting
Gastrointestinal discomfort
Dizziness and fatigue
Headache
low blood pressure upon standing
How Bromocriptine works
Bromocriptine is a dopamine receptor agonist.
It works by stimulating dopamine D2 receptors in the brain. This stimulation suppresses prolactin release from the anterior pituitary gland and reduces growth hormone secretion. The neural pathways of the brain are modulated due to this action. In the case of Type 2 diabetes, Bromocriptine aids in improving insulin sensitivity and glucose metabolism by resetting central glucose sensors and reducing sympathetic tone.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Bromocriptine is available in the form of (tablets and capsules).
Age and Dose Restrictions
This medicine is meant for adults and adolescent children above 16 years of age.
Contraindications
Bromocriptine is contraindicated in patients with known allergies to ergot derivatives. Patients with uncontrolled hypertension or those with ischemic heart disease should not take this medicine.
Other Medications to Avoid
Bromocriptine can interact with dopamine antagonists (such as metoclopramide and amoxapine), ergot alkaloids (such as ergotamine and dihydroergotamine), and macrolide antibiotics (such as erythromycin and clarithromycin).
Overdose and Missed Dose
An overdose of Bromocriptine can cause severe side effects like hallucinations or heart problems. If suspected, seek immediate medical attention.
In case you miss a dose, take it as soon as you remember. However, if it is time for the next dose, skip the missed one and continue with your regular dosage schedule. Do not double the dose to make up for the missed one.
Management of Side Effects
Most side effects of Bromocriptine are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For nausea or vomiting, try taking Bromocriptine with food.
For dizziness or lightheadedness, get up slowly from a sitting or lying position.
Maintain adequate hydration to avoid constipation.
Use in Driving and Operating Machinery
Bromocriptine may cause dizziness, drowsiness, or blurred vision in some patients. If you experience these effects, avoid driving or operating machinery.
Use in Pregnancy and Lactation
It is advised to consult a doctor before using Bromocriptine during pregnancy and breastfeeding. The doctor will evaluate the benefits and risks before recommending this medicine.
Caution in Other Conditions
Caution is advised for patients with a history of cardiovascular disease, as Bromocriptine may increase the risk of certain heart conditions. Patients with liver disease should exercise caution when taking this medicine, as it may worsen their condition.
Special Dietary and Lifestyle Recommendations
A diet rich in fruits, vegetables, whole grains, lean proteins, and low-fat dairy can help manage conditions like diabetes and high prolactin levels.
Frequently asked questions
Does Bromocriptine have any effect on sleep?
Bromocriptine can cause drowsiness and fatigue as common side effects. If you notice that this medicine is affecting your sleep patterns or causing excessive drowsiness, discuss this with your doctor.
Will Bromocriptine affect fertility?
Yes, Bromocriptine is used to manage conditions related to elevated prolactin levels, such as infertility. By reducing the level of prolactin, it can improve fertility in both men and women.
Is it safe to take Bromocriptine daily?
The safety of daily use of Bromocriptine depends on your health condition and the dosage prescribed by your doctor. Always follow your doctor's instructions regarding the frequency and duration of use.
How much time does Bromocriptine take to work?
The time taken for Bromocriptine to show its effects can vary depending on the condition being managed. Your doctor will provide you with more detailed information based on your specific situation.
What is the best time to take Bromocriptine?
Generally, Bromocriptine should be taken as directed by your doctor. The timing can depend on factors such as the condition being managed and your individual response to the medication.
Is it necessary to have a prescription for Bromocriptine?
Yes, it is necessary to have a prescription from a doctor to obtain medicines containing Bromocriptine since its dosage and usage may vary depending on the individual's condition.
Are there alternatives for Bromocriptine medication?
Though there are other dopamine receptor agonists available in the market, it is not advisable to switch medications without consulting your doctor, as each has its own set of benefits and side effects.
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