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Benzalkonium Chloride + Brimonidine

Uses of Benzalkonium Chloride + Brimonidine

  • The main use of Benzalkonium Chloride + Brimonidine is to manage intraocular pressure (IOP) in patients who have open-angle glaucoma or ocular hypertension. It belongs to the class of medications known as alpha-2 adrenergic receptor agonists.

Side effects of Benzalkonium Chloride + Brimonidine

  • Dryness of the mouth

  • Redness in the eye (ocular hyperemia)

  • Burning sensation in the eyes

  • Headache

  • Blurred vision

How Benzalkonium Chloride + Brimonidine works

  • Benzalkonium Chloride + Brimonidine is a combination medication widely used in ophthalmology.

  • Brimonidine is an alpha-2 adrenergic receptor agonist. This means it acts on specific receptors in the eye, resulting in decreased production of the fluid known as aqueous humour and increased drainage of this fluid from the eye. The net effect is a decrease in intraocular pressure (IOP), which is beneficial for conditions like open-angle glaucoma and ocular hypertension.

  • Benzalkonium Chloride, on the other hand, is a quaternary ammonium compound. It serves as a preservative, maintaining the stability of the solution and providing antimicrobial activity to prevent contamination.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Benzalkonium Chloride + Brimonidine can be used topically (eye drops).

Age and Dose Restrictions

  • This medicine is primarily intended for use in adults. It is contraindicated in neonates and infants under 2 years of age due to the risk of severe systemic toxicity.

Contraindications

  • Benzalkonium Chloride + Brimonidine is contraindicated in patients with a known allergy to either Benzalkonium Chloride or Brimonidine. It is also contraindicated in patients with severe cardiovascular disease, cerebrovascular disease, and Raynaud's phenomenon.

Other Medications to Avoid

  • Benzalkonium Chloride + Brimonidine may interact with other ocular medications, including intraocular pressure-lowering agents (such as timolol), other eye drops containing preservatives (like thimerosal), and anti-inflammatory eye drops (such as prednisolone).

Overdose and Missed Dose

  • In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

  • If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose. Do not double the dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If stinging or burning is bothersome, gently flush your eyes with clean, lukewarm water to alleviate discomfort.

  • Use sunglasses to protect your eyes from bright light and glare, especially when outdoors or in bright environments.

Use in Driving and Operating Machinery

  • Benzalkonium Chloride + Brimonidine may cause fatigue or drowsiness. Avoid driving or operating heavy machinery if you feel dizzy or tired after instilling the eye drops.

Use in Pregnancy and Lactation

  • Consult your doctor before using Benzalkonium Chloride + Brimonidine during pregnancy or breastfeeding.

Caution in Other Conditions

  • Patients with conditions such as advanced cardiovascular disease, renal impairment, hepatic impairment, major depression, and Parkinson's disease should exercise caution when using Benzalkonium Chloride + Brimonidine.

Special Dietary and Lifestyle Recommendations

  • A balanced diet rich in fruits and vegetables can support overall eye health.

  • Regular eye exercises can help maintain good vision.

  • Regular check-ups are important to monitor intraocular pressure.

  • Protect your eyes from direct exposure to sunlight.

Frequently asked questions

No, Benzalkonium Chloride + Brimonidine is not a steroid. This combination medication is used primarily in ophthalmology for managing intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Yes, one of the potential side effects of Benzalkonium Chloride + Brimonidine is drowsiness or fatigue. Therefore, it can potentially affect your sleep. It is recommended that you consult your doctor if you experience such side effects.

Benzalkonium Chloride + Brimonidine is not associated with affecting fertility. However, if you have concerns about this, it would be best to discuss them with your doctor.

The safety of daily use of Benzalkonium Chloride + Brimonidine depends on your specific medical condition and should be determined by your doctor based on your individual needs and overall health status.

The brimonidine component of Benzalkonium Chloride + Brimonidine is rapidly absorbed into the eye, with peak concentrations achieved within 1-4 hours after ocular administration.

Benzalkonium Chloride + Brimonidine is typically administered as directed by the doctor, with doses spaced 8 hours apart. Your doctor will provide specific instructions based on your individual needs.

There are no direct natural alternatives to Benzalkonium Chloride + Brimonidine that can effectively lower intraocular pressure in the same way. It is advised you consult your doctor before starting any alternative therapy.

Terms & Conditions


Benzalkonium Chloride + Brimonidine in other salts

BRIMONIDINE + TIMOLOLBENZALKONIUM CHLORIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINEBENZALKONIUM CHLORIDE + ZINC OXIDEBENZALKONIUM CHLORIDE + BROMFENAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + OFLOXACINBENZALKONIUM CHLORIDE + CYCLOPENTOLATEBENZALKONIUM CHLORIDE + CIPROFLOXACINBENZALKONIUM CHLORIDE + CIPROFLOXACIN + DEXAMETHASONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONE + TOBRAMYCINBENZALKONIUM CHLORIDE + GATIFLOXACINBENZALKONIUM CHLORIDE + DEXAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + NEPAFENACBENZALKONIUM CHLORIDE + MOXIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + TOBRAMYCINBENZALKONIUM CHLORIDE + CHOLINE SALICYLATEBENZALKONIUM CHLORIDE + DEXAMETHASONE + TOBRAMYCINBENZALKONIUM CHLORIDE + BRIMONIDINE + TIMOLOLALCAFTADINE + BENZALKONIUM CHLORIDEBRIMONIDINEBENZALKONIUM CHLORIDE + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + FLUCONAZOLEBENZALKONIUM CHLORIDE + KETOROLAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + LATANOPROSTBENZALKONIUM CHLORIDE + OLOPATADINE HYDROCHLORIDEBRIMONIDINE + OXYCHLORO COMPLEXBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEBENZALKONIUM CHLORIDE + BEPOTASTINEBENZALKONIUM CHLORIDE + BRIMONIDINE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + BIMATOPROSTBENZALKONIUM CHLORIDE + BIMATOPROST + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDE + TIMOLOLBRIMONIDINE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + CYCLOSPORINBENZALKONIUM CHLORIDE + KETOROLAC + OLOPATADINEBENZALKONIUM CHLORIDE + DORZOLAMIDEBENZALKONIUM CHLORIDE + DORZOLAMIDE + TIMOLOLBENZALKONIUM CHLORIDE + GATIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + LATANOPROST + TIMOLOLBENZALKONIUM CHLORIDE + LOTEPREDNOLBENZALKONIUM CHLORIDE + LOTEPREDNOL + TOBRAMYCINBENZALKONIUM CHLORIDE + DEXAMETHASONE + MOXIFLOXACINBENZALKONIUM CHLORIDE + LOTEPREDNOL + MOXIFLOXACINBENZALKONIUM CHLORIDE + BROMFENACBENZALKONIUM CHLORIDE + MOXIFLOXACINBENZALKONIUM CHLORIDE + OLOPATADINEBENZALKONIUM CHLORIDE + PREDNISOLONEBENZALKONIUM CHLORIDE + TIMOLOL + TRAVOPROSTBENZALKONIUM CHLORIDE + TRAVOPROSTBENZALKONIUM CHLORIDE + NATAMYCINBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + NETARSUDILBRIMONIDINE + OXYCHLORO COMPLEX + TIMOLOLBENZALKONIUM CHLORIDE + GANCYCLOVIR
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