Azilsartan Medoxomil + Chlorthalidone is primarily used to manage high blood pressure (hypertension) and belongs to the group of angiotensin II receptor blockers (ARBs) and thiazide-like diuretics.
It is also indicated for use in adults who may need multiple medications to reach their blood pressure goals or when monotherapy with either azilsartan medoxomil or chlorthalidone is not sufficient.
Dizziness
Fatigue
Diarrhoea
Flu-like symptoms
Sinusitis
Azilsartan Medoxomil + Chlorthalidone is a combination medicine used to manage high blood pressure.
Azilsartan Medoxomil is an angiotensin II receptor blocker (ARB). It functions by blocking the binding of a hormone called angiotensin II to receptors in certain body tissues. This results in the relaxation and widening of blood vessels, thus lowering blood pressure.
Chlorthalidone is a thiazide-like diuretic, which functions by increasing the amount of salt and water expelled from the body through the kidneys. This decreases the volume of fluid flowing through blood vessels, which helps to lower blood pressure.
Doctor of Medicine
BMS, FMC, MD Resident
Azilsartan Medoxomil + Chlorthalidone is available for use as tablets, which is taken orally.
This medicine is intended for use in adults.
The medicine is contraindicated in patients with an inability to produce urine (anuria).
It is also contraindicated in individuals with known hypersensitivity to any component of this product.
Azilsartan Medoxomil + Chlorthalidone may interact with other blood pressure lowering medicines (such as amlodipine, enalapril), potassium-sparing diuretics (such as spironolactone, eplerenone), and NSAIDs (such as ibuprofen, naproxen). It can also interact with lithium-containing medications and certain diabetes medications (such as metformin, insulin).
Overdosage of Azilsartan Medoxomil + Chlorthalidone may lead to low blood pressure, electrolyte imbalances, and dehydration. If such symptoms occur, immediate medical attention should be sought.
If you miss a dose of this medicine, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage dizziness and fatigue.
Resting or lying down can help manage dizziness.
Eating small meals frequently can help manage nausea.
Azilsartan Medoxomil + Chlorthalidone may cause dizziness or fatigue. If you experience these side effects, avoid driving or operating machinery.
Azilsartan Medoxomil + Chlorthalidone can cause harm to the foetus when administered to a pregnant woman. Discontinue the medicine as soon as possible once pregnancy is detected.
It is not known if azilsartan is excreted in human milk, but chlorthalidone is. Consult your doctor before using this medicine while breastfeeding.
Patients with impaired renal function should use Azilsartan Medoxomil + Chlorthalidone with caution.
Patients with conditions associated with changes in electrolyte levels, like hypokalemia (low potassium levels) and hyperuricemia (high uric acid levels), should take this medicine with caution.
Limiting the consumption of salt can help manage high blood pressure.
Regular physical activity, such as walking or cycling, can also aid in controlling blood pressure.
Avoiding alcohol and tobacco can contribute to better management of hypertension.
Frequently asked questions
Azilsartan Medoxomil + Chlorthalidone is primarily used to manage high blood pressure or hypertension.
There are no known natural alternatives that can substitute the medical effects of this medicine. Always consult your doctor before making any changes to your treatment plan.
While it is not commonly reported, some patients may experience mood changes while taking this medicine. If you experience any such symptoms, consult your doctor immediately.
This may vary depending on individual metabolic differences. Your doctor can provide a more accurate estimate based on your medical history and the specifics of your treatment plan.
Yes, this combination is intended for daily use as prescribed by your doctor to effectively control blood pressure over time.
There is no evidence to suggest that this medicine affects menstrual cycles. If you notice any changes while taking this medicine, consult your doctor.
Since this medication can affect kidney function, it should be used with caution in patients with renal impairment. Regular monitoring of kidney function may be required.
Azilsartan Medoxomil + Chlorthalidone in other salts
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