The primary use of Azelnidipine is to manage hypertension (high blood pressure). It belongs to the class of medicines known as dihydropyridine calcium channel blockers.
Apart from this principal use, it may also be used in secondary management for conditions like angina pectoris (chest pain due to heart problems) and for stroke prevention. Some doctors prescribe it to improve cardiovascular outcomes after a heart attack.
Dizziness
Headache
Peripheral oedema (swelling in ankles and feet)
Flushing
Gingival hyperplasia (gum enlargement)
Azelnidipine is a calcium channel blocker belonging to the dihydropyridine class.
It works by preventing the entry of calcium into heart and blood vessel muscle cells. This results in the relaxation and widening of blood vessels, known as vasodilation.
Doctor of Medicine
BMS, FMC, MD Resident
Azelnidipine is available for use via oral route in the form of tablets.
This medication is usually prescribed for adults. The specific age range for use should be determined by a doctor.
Azelnidipine should not be used in patients with known hypersensitivity to dihydropyridine calcium channel blockers or any other component of the formulation.
Azelnidipine can interact with antifungal medications (itraconazole and miconazole), HIV protease inhibitors (ritonavir and indinavir), antiepileptics (phenytoin and phenobarbital), cholesterol-lowering medications (simvastatin), heart medications (digoxin), and antibiotics (rifampicin).
An overdose of Azelnidipine could cause hypotension and rapid heart rate. Immediate medical attention should be sought if an overdose is suspected.
If a dose of Azelnidipine is missed, take it as soon as possible. However, if it is nearly time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for the missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.
To manage dizziness, avoid sudden changes in position.
Drinking plenty of water may help manage headaches and flushing.
Elevating feet can help manage peripheral edema (swelling).
Azelnidipine may cause dizziness. If you experience this side effect, refrain from driving or operating heavy machinery until you feel fully alert.
Azelnidipine should be used during pregnancy and lactation only if the potential benefit justifies the potential risk to the baby. Consult your doctor before using this medication in pregnancy and breastfeeding.
Patients with severe liver dysfunction should exercise caution when taking Azelnidipine.
Adopt a diet high in fruits, vegetables, whole grains, and low-fat dairy products.
Limit intake of foods high in saturated fats, cholesterol, and sodium.
Engage in regular physical activity such as walking, cycling, or swimming.
Maintain a healthy weight.
Limit consumption of alcohol and avoid smoking.
Control other health conditions such as diabetes and high cholesterol.
Frequently asked questions
Azelnidipine does not usually affect sleep. However, if you experience sleep disturbances after starting the medicine, consult your doctor.
There is no evidence that Azelnidipine affects fertility in men or women. However, if you have concerns, please consult your doctor.
Azelnidipine starts showing its effects within a few hours of administration, with peak effect seen in 2-4 hours.
Azelnidipine requires a prescription from your doctor and is not available over the counter.
The composition of the tablet would determine whether it is suitable for vegetarians or vegans. Please consult with your pharmacist or doctor for detailed information.
No evidence suggests that patients develop tolerance to the blood pressure-lowering effects of Azelnidipine over time.
Azelnidipine does not cause addiction as it does not act on the brain's reward pathways. It is a prescription medicine used to manage hypertension and angina.
Azelnidipine in other salts
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