Azelastine
Uses of Azelastine
The primary use of Azelastine is to manage symptoms of allergic rhinitis and conjunctivitis. It belongs to the class of antihistamine medications.
Besides these main uses, it is also used to provide relief from the symptoms of vasomotor rhinitis, a non-allergic form of rhinitis. In some countries, Azelastine can be used, along with other medicines, to manage symptoms of allergic asthma.
Side effects of Azelastine
Bitter taste in the mouth
Nasal discomfort and irritation
Sneezing and runny nose
Headache
Sleepiness or fatigue
How Azelastine works
Azelastine is a second-generation antihistamine, a type of medicine that fights allergies.
Its primary action is to block the effects of histamine, a substance released by the body during allergic reactions. Histamine attaches to H1 receptors causing symptoms like inflammation and itching. By binding to these H1 receptors, Azelastine stops histamine from exerting its effects.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Azelastine is available for use via nasal route in the form of a nasal spray.
It is also available for ophthalmic use in the form of eye drops.
Age and Dose Restrictions
Azelastine in the form of a nasal spray can be used by adults and children who are six years of age or older. The eye drops can be used in children who are four years and older under medical supervision.
Contraindications
Azelastine is contraindicated in patients who have known hypersensitivity to the medication or any of its ingredients.
Other Medications to Avoid
Azelastine may interact with antacids (such as cimetidine), CNS depressants (such as alcohol, sleeping pills, muscle relaxants, and psychiatric medications) and antiretroviral medicines (such as ritonavir).
Overdose and Missed Dose
Overdose of Azelastine may cause excessive drowsiness. If you suspect an overdose, immediately seek medical attention.
If you forget to administer a dose of Azelastine, do so as soon as you remember. But if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To minimise bitter taste and nasal discomfort while using the nasal spray, tilt your head forward while spraying and avoid breathing in deeply. Rinse your mouth after use.
If you experience nosebleeds, avoid spraying directly onto the nasal septum.
Use in Driving and Operating Machinery
Azelastine may cause drowsiness or dizziness, which could affect your ability to drive or operate machinery. If you experience these side effects, avoid such activities until you are sure you can perform them safely.
Use in Pregnancy and Lactation
Azelastine should only be used during pregnancy and breastfeeding if needed and the benefits outweigh the risks.
Caution in Other Conditions
Patients with mild to moderate kidney disease should exercise caution when using the nasal spray form of Azelastine. It is not advised in severe kidney dysfunction.
Special Dietary and Lifestyle Recommendations
Regular cleaning of your living environment can help manage allergic rhinitis symptoms.
Try to identify and avoid known allergens that cause your allergic symptoms.
Keep your home free from dust mites by regularly washing bedding and stuffed toys.
Frequently asked questions
Is Azelastine a steroid?
No, Azelastine is not a steroid. It is an antihistamine medication used primarily for managing symptoms of allergic rhinitis and conjunctivitis.
Does Azelastine have any effect on sleep?
Yes, one of the side effects of Azelastine can be sleepiness or fatigue. It is important to observe how your body reacts to the medicine and consult your doctor if you experience excessive sleepiness.
Can Azelastine cause weight gain?
Weight gain is not a common side effect of Azelastine. However, if you notice unexpected weight gain while using this medication, it is advisable to consult your doctor.
How quickly does Azelastine work?
Azelastine tends to work quite quickly. Some people may notice symptom relief within 15 to 30 minutes of using the spray. However, its full effects might be experienced after a few days of regular use.
Is Azelastine available over the counter, or do I need a prescription?
Typically, medicines like Azelastine are not available over the counter and require a doctor's prescription.
Does Azelastine have any known effect on mood?
No, Azelastine does not have any known effects on mood. It is primarily an antihistamine used to manage allergic rhinitis and conjunctivitis.
Does Azelastine cause dependence or withdrawal symptoms?
No, Azelastine does not cause dependence or withdrawal symptoms. It can be safely discontinued when no longer needed.
Azelastine in other salts
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