Azelaic Acid
Uses of Azelaic Acid
- Azelaic Acid is used to treat mild to moderate acne vulgaris and rosacea. The cream treats inflamed acne, while the foam and gel are for mild to moderate rosacea.
- It also helps reduce acne-related inflammation, improve skin texture, and treat melasma by reducing dark skin patches.
Side effects of Azelaic Acid
Skin reactions including burning sensation
Stinging sensation on skin
Itching on the application area
Redness of skin
In rare cases, hypopigmentation (lightening of skin colour)
How Azelaic Acid works
Azelaic Acid is a dicarboxylic acid used in dermatological formulations.
It exhibits antimicrobial activity that inhibits the growth of Propionibacterium acnes, a bacteria associated with acne, helping to reduce its occurrence.
Azelaic Acid possesses anti-inflammatory properties. It curbs the production of reactive oxygen species and restrains the release of pro-inflammatory cytokines, substances that contribute to inflammation and swelling.
Additionally, it normalizes keratin production and encourages the turnover of skin cells. This assists in unclogging pores and thwarting the formation of comedones (blocked hair follicles), thereby preventing acne development.
Certified content
Written By
BDS, MDS
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Azelaic Acid is available for use via the topical route in the form of creams, gels, and foams.
Age and Dose Restrictions
Azelaic Acid is generally safe for use in adults and children aged 12 years and above.
Contraindications
Azelaic Acid is contraindicated in individuals who have a known hypersensitivity to it or any of the components in its formulations.
It is also contraindicated for patients with a history of severe atopic dermatitis, as they may experience intensified skin irritation.
Other Medications to Avoid
This medicine may interact with other topical treatments such as retinoids (including tretinoin and adapalene) and benzoyl peroxide (a topical antibiotic), which may increase skin irritation.
Overdose and Missed Dose
Overdose of Azelaic Acid is unlikely as it is intended for external use only. Using the prescribed dosage is recommended to avoid any side effects.
If you miss a dose, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed one and continue with your regular schedule. Do not apply extra medicine to make up for a missed dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage skin irritation, like a burning or stinging sensation, apply a moisturiser before applying the medicine.
If you experience dry skin, make sure you drink an ample amount of water to keep your skin hydrated.
Use in Driving and Operating Machinery
This medicine does not affect your ability to drive or operate machinery.
Use in Pregnancy and Lactation
It is generally considered safe during pregnancy and breastfeeding. However, it is advisable to consult a doctor before using this medicine during these periods.
Caution in Other Conditions
Individuals with a sensitive skin type should exercise caution when using this medicine, as it may increase the risk of skin irritation.
Special Dietary and Lifestyle Recommendations
Practice a good skincare routine by cleansing and moisturising your skin daily.
Limit sun exposure and always use a broad-spectrum sunscreen when going outdoors as it may make your skin more sensitive to sunlight.
Avoid using harsh soaps or cleansers as it may increase skin irritation when using Azelaic Acid.
For individuals managing conditions like acne or rosacea, maintaining a gentle skincare routine is crucial. Avoid harsh scrubs or exfoliants which can aggravate the skin.
Frequently asked questions
Can Azelaic Acid be used to manage other skin conditions apart from acne?
Yes, besides managing acne, it can also be effectively used to manage rosacea and melasma, a condition characterised by dark patches on the skin.
Does Azelaic Acid have any effect on skin pigmentation?
It has been shown to reduce post-inflammatory hyperpigmentation associated with acne. However, in rare cases, it may cause hypopigmentation or lightening of skin colour, particularly in individuals with darker skin tones.
Can I use Azelaic Acid for a long period?
Yes, it is generally considered safe for long-term use. It is well-tolerated by most patients and does not lead to bacterial resistance.
Does Azelaic Acid have any anti-ageing benefits?
While it is not specifically known for anti-ageing properties, its ability to improve skin texture and reduce inflammation can contribute to an overall healthier and rejuvenated appearance of the skin.
Is Azelaic Acid safe for all skin types?
Yes, it is generally safe for use on all skin types. However, individuals with sensitive skin or a history of atopic dermatitis may experience irritation and should use the product with caution.
Can I apply other topical acne treatments along with Azelaic Acid?
While it can be used along with other topical or oral acne treatments, it is recommended to consult your doctor for the appropriateness of combination therapy, as this may increase the risk of skin irritation.
Is Azelaic Acid a steroid?
No, Azelaic Acid is not a steroid.
Azelaic Acid in other salts
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