Atorvastatin + Fenofibrate
HYPOLIPIDEMIC DRUGSUses of Atorvastatin + Fenofibrate
- Atorvastatin + Fenofibrate are used together to treat high lipid levels, including elevated cholesterol and triglycerides, and to prevent heart diseases and blockages in blood vessels.
- Atorvastatin is a statin that reduces bad cholesterol (LDL) and increases good cholesterol (HDL), while Fenofibrate helps lower triglyceride levels.
Side effects of Atorvastatin + Fenofibrate
- Constipation
- Flatulence
- Headache
- Nausea
- Stomach pain
- Muscle pain
How Atorvastatin + Fenofibrate works
- Atorvastatin is a statin that lowers cholesterol by inhibiting an enzyme called HMG-CoA reductase, which is involved in the production of cholesterol in the liver. This results in reduced levels of LDL (bad cholesterol) and overall cholesterol in the blood.
- Fenofibrate is a fibrate that works by activating peroxisome proliferator-activated receptors (PPARs), which help to lower triglyceride levels and increase HDL (good cholesterol). It also improves the breakdown of fats in the bloodstream.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Atorvastatin + Fenofibrate is available for use via the oral route (tablets).
Age and Dose Restrictions
- This combination is meant for adults and children above 10 years of age.
Contraindications
- Atorvastatin + Fenofibrate is contraindicated in patients with known allergies to atorvastatin, or fenofibrate, who have severe liver or kidney disease, disease of gallbladder or pancreas.
Overdose and Missed Dose
- Overdose of this combination can cause diarrhoea and nausea. Inform your doctor regarding these effects and follow the advice accordingly.
- If you forget to take this combination, take it as soon as you remember. But avoid repeating the dose.
Use In Driving And Operating Machinery
- This combination may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy after taking this combination.
Use in Pregnancy and Lactation
- Atorvastatin + Fenofibrate is not recommended during pregnancy or breastfeeding.
Other Medications To Avoid With This Medicine
- Using Atorvastatin + Fenofibrate in combination with oral anticoagulants (coumarin, warfarin), anti-gout medications (colchicine), antibiotics (cephalexin, tetracycline, gentamicin), antifungals (miconazole, fluconazole, ketoconazole), HIV medications (abacavir, retrovir, tenofovir), hepatitis C medications (ribavirin, elbasvir), contraceptive medications, anti-arthritis medications (cyclosporin), and other fibrates medications (clofibrate, gemfibrozil, ezetimibe) is not recommended. Before using any prescription or over-the-counter medications, consulting with your doctor is imperative.
Special Dietary & Lifestyle Recommendation
- Avoid alcohol when you are taking Atorvastatin + Fenofibrate.
- Individuals with a history of heart disease should consider lifestyle modifications, including dietary changes such as adopting a low-carbohydrate and low-fat diet in conjunction with Atorvastatin + Fenofibrate.
- Avoid taking grapefruit juice along with Atorvastatin + Fenofibrate.
Frequently asked questions
1. How much time does Atorvastatin + Fenofibrate take to work?
This combination starts showing its effect within a few hours after consumption.
2. What warnings and precautions should I take while taking Atorvastatin + Fenofibrate?
Avoid using this combination if consuming fatty products or grapefruit juice, as due to potential interactions, the combination may elevate the risk of severe adverse effects, including muscular complications.
3. Can I stop taking Atorvastatin + Fenofibrate if I feel healthy?
Do not stop taking this combination without consulting your doctor, even if you feel healthy.
4. Is it safe for patients with kidney or liver issues?
Consult your doctor before taking this combination if you have kidney or liver issues to ensure its safety and proper dosage.
Atorvastatin + Fenofibrate in other salts
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