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Amoxicillin + Clarithromycin + Pantoprazole

Uses of Amoxicillin + Clarithromycin + Pantoprazole

  • Amoxicillin + Clarithromycin + Pantoprazole is primarily used to manage peptic ulcer disease caused by Helicobacter pylori infection. It belongs to the group of antibiotics and proton pump inhibitors.

Side effects of Amoxicillin + Clarithromycin + Pantoprazole

  • Diarrhoea

  • Headache

  • Nausea

  • Abdominal pain

  • Vomiting

How Amoxicillin + Clarithromycin + Pantoprazole works

  • Amoxicillin, being a penicillin-type antibiotic, interferes with the construction of bacterial cell walls, leading to their collapse and eventual death.

  • Clarithromycin, which is a macrolide antibiotic, halts the growth of bacteria by suppressing their protein synthesis, which is essential for continued bacterial growth and reproduction.

  • Pantoprazole, categorized as a proton pump inhibitor, reduces the production of stomach acid by obstructing the proton pumps present in the gastric parietal cells. This action reduces acid-related damage to the stomach and duodenum. Together, these three components work towards eradicating H. pylori infection and promoting ulcer healing.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Amoxicillin + Clarithromycin + Pantoprazole is available in the form of tablets. This medicine is used via the oral route.

Age and Dose Restrictions

  • This medicine is meant for adults.

Contraindications

  • This medicine is contraindicated in patients with known allergies to amoxicillin, clarithromycin, or pantoprazole.

  • It should not be used by patients with a history of cholestatic jaundice or hepatic dysfunction associated with prior clarithromycin use.

  • The combination therapy is also contraindicated in severe hepatic impairment and those taking rilpivirine-containing products.

Other Medications to Avoid

  • Amoxicillin + Clarithromycin + Pantoprazole may interact with allopurinol (like Zyloprim and Lopurin), oral contraceptives (such as Ethinylestradiol + Levonorgestrel), probenecid (such as Probalan), and medicines metabolised by CYP2C19 (e.g., clopidogrel and citalopram).

Overdose and Missed Dose

  • Overdosing on this medication could lead to serious health complications. In such instances, immediate medical help should be sought. Vital signs monitoring and supportive care are important in managing an overdose situation.

  • If you miss a dose, take it as soon as you remember, unless it's nearly time for your next dose. Avoid doubling up on doses to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can help manage some side effects like dry mouth and constipation.

  • Taking this medication with food can reduce the occurrence of stomach discomfort or nausea.

Use in Driving and Operating Machinery

  • This medicine may cause dizziness or disorientation. If you experience these side effects, avoid driving or operating heavy machinery until you feel able to perform these tasks safely.

Use in Pregnancy and Lactation

  • Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding.

Caution in Other Conditions

  • This medicine should be used with caution in patients with severe hepatic impairment due to the presence of clarithromycin.

  • Caution is also advised in patients who have a known history of hypersensitivity reactions to any of the individual components of this combination.

  • This combination should be used with caution in patients with severe renal impairment. 

Special Dietary and Lifestyle Recommendations

  • A diet rich in fiber may help manage potential gastrointestinal issues associated with this medicine.

  • Regular rest is important as this medicine may sometimes cause dizziness or disorientation.

  • A balanced diet along with regular exercise, can also help improve overall health and well-being.

Frequently asked questions

No, this medication does not contain any steroids. It comprises an antibiotic and a proton pump inhibitor.

Amoxicillin + Clarithromycin + Pantoprazole is not directly associated with affecting mood. However, as with any medication, if you experience any unusual emotional or mood-related effects, consult your doctor right away.

Yes, it is crucial to complete the full course of Amoxicillin + Clarithromycin + Pantoprazole to ensure complete eradication of the H. pylori bacteria and to prevent the recurrence of the ulcers.

Amoxicillin + Clarithromycin + Pantoprazole is not associated with affecting the menstrual cycle. However, if you notice any irregularities while taking this medication, consult your doctor.

Yes, Amoxicillin + Clarithromycin + Pantoprazole does not contain any animal-derived ingredients and can be taken by vegetarians and vegans. However, always check the label for any specific allergens or ingredients you may want to avoid.

No, this medicine typically requires a prescription from a doctor. Never self-medicate, and always consult your doctor before taking any medication.

Neither weight gain nor weight loss are commonly associated with this medication. However, if you notice significant changes in your weight while taking this medicine, it is advisable to consult your doctor.

Terms & Conditions


Available medicines for AMOXICILLIN + CLARITHROMYCIN + PANTOPRAZOLE
Pantop Hp Kit Tablet 6
Pantop Hp Kit Tablet 6
Aristo Pharmaceuticals Pvt.ltd
Pack of 6 Units
₹176.30
MRP ₹215.00
18.00% OFF
Evoxil Hp Kit 750/40/500mg Tablet 6
Evoxil Hp Kit 750/40/500mg Tablet 6
Leeford Healthcare
Pack of 6 Units
₹86.30
MRP ₹163.00
47.06% OFF
Neo Hp Kit 1
Neo Hp Kit 1
Parnasa Mediworld Pvt Ltd
Pack of 1 Units
₹155.80
MRP ₹190.00
18.00% OFF
Cavmox Hp Kit 4 Tablet And 2 Capsule
Cavmox Hp Kit 4 Tablet And 2 Capsule
Leeford Healthcare
Pack of 6 Units
₹61.50
MRP ₹75.00
18.00% OFF
Pleze Hp 750/40/500 MG Kit 1
Pleze Hp 750/40/500 MG Kit 1
Lifeline Remedies India Pvt Ltd
Pack of 1 Units
₹122.92
MRP ₹149.90
18.00% OFF
My Hp Kit 1
My Hp Kit 1
Mrl Pharma Pvt Ltd.
Pack of 1 Units
₹177.94
MRP ₹217.00
18.00% OFF
Pantostrum Hp Kit Tablet 6
Pantostrum Hp Kit Tablet 6
Steris Healthcare
Pack of 6 Units
₹84.83
MRP ₹170.00
50.10% OFF
Pantocid Hp Combipack Tablet 6
Pantocid Hp Combipack Tablet 6
Sun Pharma Laboratories Ltd.
Pack of 6 Units
₹178.76
MRP ₹218.00
18.00% OFF

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