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Amlodipine

ANTIHYPERTENSIVE

Uses of Amlodipine

  • Amlodipine is used to treat high blood pressure in adults and children aged 6 years and older. 
  • It is primarily used for the management of hypertension and is also effective in managing various types of coronary artery disease, such as angina.

Side effects of Amlodipine

The side effects of Amlodipine are:

  • Fatigue
  • Nausea
  • Abdominal pain
  • Sleepiness
  • Headache

How Amlodipine works

Amlodipine is a medication used to treat high blood pressure (hypertension) and chest pain (angina). It belongs to a class of drugs called calcium channel blockers. 

Here’s a detailed explanation of its mechanism of action:

  • Amlodipine inhibits the influx of calcium ions through the L-type calcium channels found in the smooth muscle cells of the blood vessels and the heart.
  • By blocking calcium entry, amlodipine causes the smooth muscles of the blood vessels to relax and dilate (widen). This vasodilation reduces the resistance the heart has to pump against, thereby lowering blood pressure.
  • In addition to lowering blood pressure, the relaxation of blood vessels reduces the workload on the heart, making it easier for the heart to pump blood.
  • For patients with angina, the widened arteries improve blood flow to the heart muscle, which helps to relieve chest pain and reduce the frequency of angina attacks.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available for Amlodipine

  • Amlodipine is available for use via the oral route (tablet and suspension).

Age And Dosage Restrictions for Amlodipine

  • This medicine is meant for adults and children above six years of age.

Contraindications of Amlodipine

  • The medication is not recommended in patients with a known hypersensitivity to amlodipine.

Medications To Avoid With Amlodipine

  • Amlodipine may interact with various medications, including those used to lower blood pressure (benazepril, metoprolol, ramipril, hydrochlorothiazide), drugs utilised to manage lipid levels in the blood (like atorvastatin simvastatin), medications for erectile dysfunction (sildenafil), antibiotics (including clarithromycin, erythromycin, rifampin), antifungal agents (such as itraconazole, ketoconazole), anti-HIV drugs (like ritonavir), anti-epilepsy medications (including carbamazepine, phenytoin, phenobarbital, primidone), immune-suppressing drugs (like cyclosporine, tacrolimus), and painkillers (such as ibuprofen, aspirin).

Overdose and Missed Dose

  • An overdose of this medication may cause symptoms like low blood pressure and increased heart rate. If you observe these symptoms, inform your doctor and follow the advice accordingly.
  • If you forget to take this medicine, take it as soon as you remember. But avoid repeating the dose.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Use in Driving and Operating Machinery

  • This medication may impair your ability to drive and operate heavy machinery.

Use in Pregnancy and Lactation

  • Amlodipine is not recommended for use in pregnancy and breastfeeding unless recommended by your doctor.

Caution in Other Conditions

  • Patients with a history of kidney or liver issues, heart diseases, and heart attack should be cautious.
  • Avoid alcohol when taking amlodipine.

Special Dietary & Lifestyle Recommendation

  • Individuals managing hypertension and heart conditions should consider lifestyle changes, including dietary adjustments such as incorporating a low-sodium, low-carbohydrate, and low-fat diet alongside amlodipine.
  • Proper education on recognising the signs and symptoms of heart attacks and strokes is essential. This knowledge can lead to quicker interventions, minimising complications and ultimately promoting a faster and more complete recovery.

Frequently asked questions

This medicine's onset of action may require a few days for full efficacy to be realised.

Avoid using amlodipine if you exhibit an allergic reaction (hypersensitivity) to it.

Please refrain from discontinuing amlodipine without consulting your doctor first. Abruptly stopping the medication may result in the return of symptoms.

Patients with kidney and liver issues should exercise caution while taking amlodipine.

Amlodipine is unlikely to affect fertility in men or women. For the most accurate, updated details, contact your doctor.

Amlodipine is not considered harmful to the kidneys. However, if you have kidney disease, your doctor will monitor your kidney function while you’re on this medication.

No, Amlodipine is not a beta-blocker. It belongs to a class of medications called calcium channel blockers. It relaxes blood vessels and lowers blood pressure without affecting heart rate.

While taking Amlodipine, be cautious when going from sitting to standing, as it may cause a drop in blood pressure. Also, avoid alcohol consumption, which can further lower blood pressure. If you experience dizziness or swelling, consult your doctor.

Swelling (edema) is a common side effect of Amlodipine. Consider wearing compression socks or elevating your legs to help manage the swelling. Inform your doctor promptly, as they may adjust your medication if needed.

Terms & Conditions


Available medicines for AMLODIPINE
Amlovas 5 Tablet 15
Amlovas 5 Tablet 15
Macleods Pharmaceuticals Pvt.ltd
Pack of 15 Units
₹34.44
MRP ₹42.00
18.00% OFF
Amlodac 5 Tablet 30
Amlodac 5 Tablet 30
Zydus Cadila
Pack of 30 Units
₹68.88
MRP ₹84.00
18.00% OFF
Amlong Tablet 30
Amlong Tablet 30
Micro Labs Ltd
Pack of 30 Units
₹66.24
MRP ₹84.00
21.14% OFF
Amlokind 5 Tablet 15
Amlokind 5 Tablet 15
Mankind Pharmaceuticals Ltd.
Pack of 15 Units
₹20.36
MRP ₹24.83
18.00% OFF
Stamlo 2.5 Tablet 30
Stamlo 2.5 Tablet 30
Dr. Reddys Laboratories Ltd
Pack of 30 Units
₹49.28
MRP ₹60.10
18.00% OFF
Amlosafe 5 Tablet 15
Amlosafe 5 Tablet 15
Aristo Pharmaceuticals Pvt.ltd
Pack of 15 Units
₹34.44
MRP ₹42.00
18.00% OFF
Amlip 5 Tablet 10
Amlip 5 Tablet 10
Cipla Ltd.
Pack of 10 Units
₹13.97
MRP ₹27.99
50.10% OFF
Stamlo 5 Tablet 30
Stamlo 5 Tablet 30
Dr. Reddys Laboratories Ltd
Pack of 30 Units
₹71.31
MRP ₹83.90
15.00% OFF

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