The primary use of Ambroxol + Guaifenesin + Levocetirizine + Phenylephrine is for the symptomatic relief of productive cough and nasal congestion due to common cold, flu, bronchitis, sinusitis and allergic rhinitis and belongs to the class of mucolytic agents, antihistamines, expectorants and decongestants.
Additionally, it is also used for reducing viscous secretions in acute and chronic inflammatory conditions of the upper and lower respiratory tract.
Drowsiness
Dry mouth or throat
Nausea
Vomiting
Rash or itching
Ambroxol belongs to the mucolytics class of medicines. It works by breaking down and thinning the thick mucus in the airways. This makes it easier to cough out the mucus and clear the airways.
Guaifenesin is an expectorant that helps to further loosen mucus in the airways. It stimulates glands in the stomach and leads to an increase in liquid secretions within the respiratory tract. This action helps to move the mucus up and out of the lungs, further aiding in clearing the airways.
Levocetirizine is an antihistamine that blocks histamine - a natural substance in our body responsible for allergic reactions. This reduces symptoms like itching, running nose and watery eyes.
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. This helps to reduce swelling and congestion, making it easier to breathe. Together, these components work synergistically to manage symptoms of conditions like common cold, flu, allergies and other respiratory troubles.
MSc (Applied Genetics)
BMS, FMC, MD Resident
Ambroxol + Guaifenesin + Levocetirizine + Phenylephrine is available in tablets, syrups, and suspension forms for oral administration.
This combination medicine is intended for adults and children.
The medicine is contraindicated in patients with known hypersensitivity to any of the ingredients present in this combination.
It should be avoided in individuals with severe hypertension, coronary artery disease, narrow-angle glaucoma, urinary retention, hyperthyroidism, diabetes mellitus, ischemic heart disease, and prostatic hypertrophy.
This medicine interacts with antihypertensive (eg., Beta-blockers and ACE inhibitors), Monoamine Oxidase Inhibitors (MAOIs) (e.g., phenelzine, tranylcypromine), Centrally Acting Sedatives (e.g., benzodiazepines, alcohol), Antidiabetic Medications (e.g., insulin, oral hypoglycemic), Anticoagulants/Antiplatelets (e.g., warfarin, aspirin), CYP3A4 Inhibitors (e.g., ketoconazole, erythromycin), and other Decongestants (e.g., pseudoephedrine, oxymetazoline).
Overdose of this combination medicine may cause symptoms such as nausea, vomiting, rapid heart rate, restlessness, drowsiness, and in severe cases, seizures. If you suspect an overdose, consult your doctor immediately.
If you miss a dose of this medicine, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Most side effects are temporary and usually resolve once the medication is discontinued. However, if side effects persist or worsen, consult a doctor.
Drinking plenty of fluids may help manage some side effects such as dry mouth or throat.
For drowsiness or dizziness, avoid activities that require alertness such as driving or operating heavy machinery until you know how this medication affects you.
This medicine can affect your ability to drive or operate heavy machines. Avoid these activities if you experience dizziness or drowsiness after taking this medicine.
The safety of this combination during pregnancy and lactation has not been fully established. It should be used in pregnant or breastfeeding women only if clearly needed and prescribed by a doctor.
Patients with severe liver or kidney disease should exercise caution while taking this medicine as it could accumulate in the body due to reduced excretion.
To manage respiratory conditions effectively, it is recommended to stay hydrated, eat a balanced diet rich in fruits and vegetables, and avoid exposure to allergens and irritants like dust, smoke, or strong odours.
Regular physical activity can also help improve lung function. However, it is important to consult a doctor before starting any new exercise regimen.
Frequently asked questions
Yes, this combination medicine is effective for managing respiratory conditions where there is excessive mucus production along with nasal congestion and runny nose. However, it should be used under the supervision of a doctor as it is aimed at symptomatic relief and not curing the underlying condition.
Yes, this composition can help manage allergy symptoms such as runny nose, sneezing, and itchy eyes due to the presence of an antihistamine.
Yes, this combination medicine is available in various formulations including tablets, syrups, and extended-release forms for easier administration.
While most side effects are generally mild and manageable, rare but serious side effects like allergic reactions, fast or irregular heartbeat, hallucinations, seizures, severe dizziness, and trouble breathing require immediate medical attention.
This medication should be used with caution in patients with narrow-angle glaucoma, urinary retention, severe hypertension or coronary artery disease, hyperthyroidism, diabetes mellitus, ischemic heart disease, and prostatic hypertrophy.
Some patients might experience drowsiness, trouble sleeping, nervousness, restlessness, or irritability as side effects of this medication.
The combination of ambroxol, guaifenesin, levocetirizine, and phenylephrine may be used in children, but caution is needed, especially due to the decongestant phenylephrine. Always consult a healthcare provider to ensure it’s safe for your child.
Ambroxol + Guaifenesin + Levocetirizine + Phenylephrine in other salts
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