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Alpha-beta Arteether + Lumefantrine

Uses of Alpha-beta Arteether + Lumefantrine

  • The primary use of Alpha-Beta Arteether + Lumefantrine is for the management of acute uncomplicated malaria caused by Plasmodium falciparum. This medication belongs to the class of antimalarial medicines.

Side effects of Alpha-beta Arteether + Lumefantrine

  • Headache

  • Muscle or joint pain

  • Nausea and vomiting

  • Abdominal pain

  • Rash

How Alpha-beta Arteether + Lumefantrine works

  • Alpha-Beta Arteether + Lumefantrine is an antimalarial combination.

  • Alpha-Beta Arteether belongs to a group known as artemisinin compounds. It works by having an active part called an endoperoxide bridge that reacts with a form of iron present in infected red blood cells.

  • Lumefantrine, another component of this medicine, is an aryl amino-alcohol. It acts by blocking the malaria parasite's ability to detoxify heme. Furthermore, it interferes with the building blocks of the parasite such as nucleic acid and protein synthesis and may disturb the parasite's digestive pathway in the lysosomes. Working together, these two components quickly reduce the load of parasites and remove any remaining ones, managing cases of acute uncomplicated malaria effectively.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Alpha-Beta Arteether + Lumefantrine is available for use via oral route in the form of tablets.

Age and Dose Restrictions

  • The medicine is indicated for adults and children.

Contraindications

  • This medicine is contraindicated in patients with known hypersensitivity to either Alpha-Beta Arteether or Lumefantrine.

  • It should not be given to infants weighing less than 5 kg or those with severe malaria.

Other Medications to Avoid

  • This combination may interact with CYP3A4 inducers (such as carbamazepine and phenytoin), CYP3A4 inhibitors (like ketoconazole and erythromycin) and medications that prolong the QT interval (such as quinine, antipsychotics, and fluoroquinolones).

Overdose and Missed Dose

  • In case of an overdose, symptoms such as headache, dizziness and palpitations may occur. If you observe such symptoms, inform your doctor immediately.

  • If you miss a dose of this medicine, take it as soon as you remember. But avoid doubling up the dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If you feel dizzy or lightheaded after taking the medication, try sitting or lying down.

  • If you experience nausea or vomiting, try taking the medication with meals.

Use in Driving and Operating Machinery

  • This medicine may cause side effects like dizziness which can affect your ability to drive or operate machines. Avoid these activities if you feel dizzy after taking the medicine.

Use in Pregnancy and Lactation

  • It is advised to consult a doctor before using Alpha-Beta Arteether + Lumefantrine during pregnancy and breastfeeding.

Caution in Other Conditions

  • Caution is advised in patients with QT prolongation and those with electrolyte imbalances.

  • Dose adjustment may be needed for hepatic and renal impairment.

Special Dietary and Lifestyle Recommendations

  • Regular consumption of a balanced diet can help boost immunity and prevent diseases like malaria.

  • Wearing protective clothing and using insect repellents can help prevent mosquito bites, thereby reducing the risk of malaria.

  • Keeping your surroundings clean and free from stagnant water can help keep mosquitoes at bay.

Frequently asked questions

No, Alpha-Beta Arteether + Lumefantrine is not a steroid. The combination is an antimalarial medication utilised for the management of acute uncomplicated malaria caused by Plasmodium falciparum.

Yes, sleep disorders have been reported as a common side effect of this combination of medications. If you experience any unusual sleep-related symptoms while using this medicine, consult your doctor.

Alpha-Beta Arteether + Lumefantrine is not associated with any significant effect on fertility. However, if you plan to conceive or are currently experiencing fertility issues, it is wise to discuss your medication use with your doctor.

It is recommended to take Alpha-Beta Arteether + Lumefantrine as per your doctor's advice, typically as a 3-day course for the management of acute malaria.

The Alpha-beta arteether component of the combination is a fast-acting agent that rapidly reduces the parasite load in the body.

The standard regimen of treatment with this combination lasts for a few days.

Alpha-Beta Arteether + Lumefantrine is a potent antimalarial medication and is typically not available without a prescription. Always consult your doctor before taking any medication.

Terms & Conditions


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