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Aciclovir / Acyclovir

Uses of Aciclovir / Acyclovir

  • Aciclovir / Acyclovir is an antiviral medication primarily used to manage infections caused by the herpes simplex virus (HSV) and the varicella-zoster virus (VZV).

  • It is also occasionally used to manage infections caused by Epstein-Barr virus (EBV) and cytomegalovirus (CMV).

Side effects of Aciclovir / Acyclovir

  • Nausea

  • Vomiting

  • Diarrhoea

  • Headaches

  • Fatigue

  • Skin rashes

How Aciclovir / Acyclovir works

  • Aciclovir / Acyclovir is an antiviral medication.

  • It interacts with a viral enzyme called thymidine kinase, converting the medication into Aciclovir triphosphate. This form, then interferes with the virus's DNA, inhibiting its ability to multiply and spread in your body.

  • The medicine exhibits a higher affinity for thymidine kinase compared to the human version of the enzyme, making it more effective on infected cells.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Aciclovir / Acyclovir is available in several formulations, like oral tablets and an oral suspension (liquid).

  • It is also available as a topical cream for skin application, an ophthalmic ointment for eye infections, and as a solution for intravenous administration.

Age and Dose Restrictions

  • This medicine is prescribed for adults and children of all age groups.

Contraindications

  • This medicine is contraindicated in patients with a known hypersensitivity to Aciclovir / Acyclovir or other similar antiviral medicines.

Other Medications to Avoid with This Medicine

  • Aciclovir / Acyclovir may interact with anticonvulsants (like fosphenytoin and phenytoin), immunosuppressants (such as sirolimus and tacrolimus), and certain antibiotics (like telavancin and vancomycin).

Overdose and Missed Dose

  • An overdose of this medicine may lead to symptoms like nausea, vomiting, headaches, and seizures. If you suspect an overdose, inform your doctor immediately.

  • If you forget to take a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary, generally harmless, and resolve once you discontinue this medicine. However, if you experience severe side effects or worsening symptoms, consult your doctor.

  • For nausea and vomiting, try taking your medicine with a meal or snack.

  • For headaches, rest, drink plenty of fluids, and get enough sleep.

Use in Driving and Operating Machinery

  • As this medicine may cause dizziness or fatigue, it is advisable to avoid driving or operating heavy machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

  • While this medicine is generally considered safe during pregnancy and breastfeeding, it is advisable to consult your doctor if you are pregnant or lactating.

Caution in Other Conditions

  • Patients with kidney problems should use this medicine with caution, as they may need dosage adjustments. This medicine is primarily eliminated by the kidneys, and high levels of this medicine could lead to further deterioration of kidney function.

Special Dietary and Lifestyle Recommendation

  • Drink enough water, especially if you're taking oral or intravenous forms of this medicine, to prevent kidney damage.

  • Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.

  • Avoid touching the infected area and then touching your eyes. Wash your hands frequently to prevent the spread of the infection.

Frequently asked questions

No, Aciclovir/AAcyclovir is an antiviral medicine used specifically to treat infections caused by certain viruses. It is not effective against the viruses that cause cold or the flu.

Yes, Aciclovir / Acyclovir can be used in children for conditions like chickenpox. However, the dosage and duration of treatment should be determined by a doctor.

No, you should continue taking the medicine for the entire duration prescribed by your doctor. Stopping the medication early may cause a relapse of the infection.

While there is no direct interaction between alcohol and this medicine, it is generally recommended to limit alcohol intake, as it can interfere with your overall health and recovery.

Some medicines may interact with Aciclovir / Acyclovir. Always inform your doctor about all medications you are currently taking.

There is no evidence that Aciclovir / Acyclovir affects mood or behaviour. If you notice any changes in your mood while on this medicine, consult your doctor.

Yes, skin rashes are one of the common side effects of this medicine. However, if you notice any unusual skin reactions, consult your doctor immediately.

Terms & Conditions

Available medicines for ACICLOVIR / ACYCLOVIR
Acivir 800 Dt Tablet 5
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Acivir 200 Dt Tablet 10
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Acivir 400 Dt Tablet 10
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Acivir 400 Dt Tablet 5
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Acivir Cream 10gm
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Herpex 5% Cream 5gm
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Zovirax 400mg Tablet 10
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